Western Blot (WB)
(Western Blot analysis in U251 cell line lysates (35ug/lane) usingMBS6006621. This demonstrates that MBS6006621 detected the YTHD2 protein (arrow).)
Rabbit anti-Human YTHD2 Polyclonal Antibody | anti-YTHD2 antibody
YTHD2, CT (YTHDF2, HGRG8, YTH domain family protein 2, CLL-associated antigen KW-14, High-glucose-regulated protein 8, Renal carcinoma antigen NY-REN-2) (AP)
Gene Names
YTHDF2; HGRG8; NY-REN-2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
YTHD2; Polyclonal Antibody; CT (YTHDF2; HGRG8; YTH domain family protein 2; CLL-associated antigen KW-14; High-glucose-regulated protein 8; Renal carcinoma antigen NY-REN-2) (AP); YTHDF2; Renal carcinoma antigen NY-REN-2; anti-YTHD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human YTHD2.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-YTHD2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 551-579 in the C-terminal region of human YTHD2, UniProt Accession #Q9Y5A9. Species sequence homology: bovine, monkey, mouse
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis in U251 cell line lysates (35ug/lane) usingMBS6006621. This demonstrates that MBS6006621 detected the YTHD2 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in U251 cell line lysates (35ug/lane) usingMBS6006621. This demonstrates that MBS6006621 detected the YTHD2 protein (arrow).)
Related Product Information for anti-YTHD2 antibody
YTHDF2 is a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.
Product Categories/Family for anti-YTHD2 antibody
References
1. Nguyen, T.T., et al. Genes Chromosomes Cancer 45(10):918-932(2006). 2. Cardelli, M., et al. J. Gerontol. A Biol. Sci. Med. Sci. 61(6):547-556(2006). 3. Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005). 4. Stoilov, P., et al. Trends Biochem. Sci. 27(10):495-497(2002). 5. Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
62,334 Da
NCBI Official Full Name
YTH domain-containing family protein 2 isoform 2
NCBI Official Synonym Full Names
YTH domain family, member 2
NCBI Official Symbol
YTHDF2
NCBI Official Synonym Symbols
HGRG8; NY-REN-2
NCBI Protein Information
YTH domain-containing family protein 2; 9430020E02Rik; CLL-associated antigen KW-14; high-glucose-regulated protein 8; renal carcinoma antigen NY-REN-2
UniProt Protein Name
YTH domain-containing family protein 2
UniProt Gene Name
YTHDF2
UniProt Synonym Gene Names
HGRG8
UniProt Entry Name
YTHD2_HUMAN
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Product Notes
The YTHD2 ythdf2 (Catalog #AAA6364380) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The YTHD2, CT (YTHDF2, HGRG8, YTH domain family protein 2, CLL-associated antigen KW-14, High-glucose-regulated protein 8, Renal carcinoma antigen NY-REN-2) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's YTHD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the YTHD2 ythdf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "YTHD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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