Western Blot (WB)
(Western blot analysis of Wnt-6 expression in rat kidney tissue lysate.)
Rabbit Wnt6 Polyclonal Antibody | anti-Wnt6 antibody
Wnt6 Antibody
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
Wnt6; Polyclonal Antibody; Wnt6 Antibody; Rabbit Polyclonal Wnt6 Antibody; Polyclonal Wnt6 antibody; anti-Wnt6 antibody; wingless-related MMTV integration site 6 antibody; antibody; Wnt 6 antibody; Wnt 6; Wnt-6; wnt-6 antibody; wnt 6 antibody; Wnt-6 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer containing 30% Glycerol, 0.5% BSA, and 0.01% Thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
338
Applicable Applications for anti-Wnt6 antibody
Western Blot (WB)
Application Notes
IHC: 10-20 ug/ml
WB: 0.5-4 ug/ml
WB: 0.5-4 ug/ml
Immunogen
Wnt6 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 276 of mouse Wnt-6 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Wnt-6 expression in rat kidney tissue lysate.)
Western Blot (WB)
(Western blot analysis of Wnt-6 expression in rat kidney tissue lysate.)
Related Product Information for anti-Wnt6 antibody
Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-6 is involved in oncogenesis and is co-expressed with Wnt10 in colorectal cancer cell lines. The presence of cervical and breast cell carcinomas may indicate an over expression of Wnt-6.
Product Categories/Family for anti-Wnt6 antibody
NCBI and Uniprot Product Information
NCBI Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008]
Research Articles on Wnt6
Similar Products
Product Notes
The Wnt6 (Catalog #AAA5311368) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Wnt6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). IHC: 10-20 ug/ml WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the Wnt6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wnt6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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