Western Blot (WB)
(Western blot analysis of WNT1 Antibody (C-term) in mouse heart tissue lysates (35ug/lane). WNT1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human, Mouse Wnt1 Polyclonal Antibody | anti-Wnt1 antibody
Wnt1, CT (Proto-oncogene Wnt-1, Proto-oncogene Int-1 Homolog, INT1) (MaxLight 405)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of WNT1 Antibody (C-term) in mouse heart tissue lysates (35ug/lane). WNT1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of WNT1 Antibody (C-term) in mouse heart tissue lysates (35ug/lane). WNT1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(WNT1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human testis followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WNT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(WNT1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human testis followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WNT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(WNT1 Antibody (C-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(WNT1 Antibody (C-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
Uniprot Description
WNT1: Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Belongs to the Wnt family.
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide; Oncoprotein; Cell development/differentiation
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; Golgi lumen; endoplasmic reticulum lumen; cytoplasm; extracellular region; plasma membrane
Molecular Function: protein domain specific binding; frizzled binding; cytokine activity; receptor agonist activity
Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; T cell differentiation in the thymus; Wnt receptor signaling pathway through beta-catenin; ubiquitin-dependent SMAD protein catabolic process; diencephalon development; negative regulation of BMP signaling pathway; neuron differentiation; cerebellum formation; positive regulation of fibroblast proliferation; cell-cell signaling; midbrain development; positive regulation of cell proliferation; midbrain-hindbrain boundary maturation during brain development; response to wounding; positive regulation of Notch signaling pathway; myoblast fusion; neuron fate determination; inner ear morphogenesis; organ regeneration; cell fate commitment; Wnt receptor signaling pathway; embryonic axis specification; DNA damage response, signal transduction; negative regulation of fat cell differentiation; central nervous system morphogenesis; ureteric bud branching; forebrain anterior/posterior pattern formation; spinal cord association neuron differentiation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; negative regulation of cell-cell adhesion; positive regulation of protein amino acid phosphorylation; negative regulation of transforming growth factor beta receptor signaling pathway; Spemann organizer formation
Disease: Bone Mineral Density Quantitative Trait Locus 16; Osteogenesis Imperfecta, Type Xv
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Product Notes
The Wnt1 wnt1 (Catalog #AAA6506133) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Wnt1, CT (Proto-oncogene Wnt-1, Proto-oncogene Int-1 Homolog, INT1) (MaxLight 405) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Wnt1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Wnt1 wnt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wnt1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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