Rabbit anti-Human WBSCR22 Polyclonal Antibody | anti-WBSCR22 antibody

WBSCR22, CT (WBSCR22, Uncharacterized methyltransferase WBSCR22, Williams-Beuren syndrome chromosomal region 22 protein) (APC)

Cat. Num. AAA6363061

• Gene Names: WBSCR22; WBMT; MERM1; PP3381; HUSSY-3; HASJ4442
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: WBSCR22; Polyclonal Antibody; CT (WBSCR22; Uncharacterized methyltransferase WBSCR22; Williams-Beuren syndrome chromosomal region 22 protein) (APC); Williams-Beuren syndrome chromosomal region 22 protein; anti-WBSCR22 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-WBSCR22 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: WBSCR22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the C-terminal region of human WBSCR22.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(WBSCR22 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the WBSCR22 antibody detected the WBSCR22 protein (arrow).)

Related Product Information for anti-WBSCR22 antibody

This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.

Product Categories/Family for anti-WBSCR22 antibody

Antibodies; Enzymes; Methyltransferase

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Andersen, J.S., et al. Nature 433(7021):77-83(2005). Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004). Merla, G., et al. Hum. Genet. 110(5):429-438(2002). Stanchi, F., et al. Yeast 18(1):69-80(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 23199995
• NCBI GeneID: 114049
• NCBI Accession #: NP_059998.2
• NCBI GenBank Nucleotide #: NM_017528.4
• UniProt Accession #: O43709; Q96P12; Q9BQ58; Q9HBP9; A8K501; C9K060
• Molecular Weight: 33,846 Da
• NCBI Official Full Name: probable 18S rRNA (guanine-N(7))-methyltransferase isoform 2
• NCBI Official Synonym Full Names: Williams-Beuren syndrome chromosome region 22
• NCBI Official Symbol: WBSCR22
• NCBI Official Synonym Symbols: WBMT; MERM1; PP3381; HUSSY-3; HASJ4442
• NCBI Protein Information: probable 18S rRNA (guanine-N(7))-methyltransferase
• UniProt Protein Name: Probable 18S rRNA (guanine-N(7))-methyltransferase
• Protein Family: Probable 18S rRNA
• UniProt Gene Name: WBSCR22
• UniProt Synonym Gene Names: MERM1
• UniProt Entry Name: WBS22_HUMAN

NCBI Description

This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been found. [provided by RefSeq, Feb 2011]