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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7130146(VPS26A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit VPS26A Polyclonal Antibody | anti-VPS26A antibody

VPS26A Antibody

Gene Names
VPS26A; HB58; PEP8A; VPS26; Hbeta58
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
VPS26A; Polyclonal Antibody; VPS26A Antibody; Vacuolar protein sorting 26 homolog A (S. pombe); anti-VPS26A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-VPS26A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
WB: 1:500-1:2000
IHC: 1:30-1:150
Immunogen
Synthetic peptide of human VPS26A
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7130146(VPS26A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7130146(VPS26A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7130146(VPS26A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7130146(VPS26A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 12%SDS-PAGE,Lysate: 40 ug,Lane 1-7: 293T cells, A431 cells, Hela cells, HepG2 cells, Human fetal liver tissue, PC3 cells, Human placenta tissue,Primary antibody: MBS7130146(VPS26A Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds)

SDS-Page (Gel: 12%SDS-PAGE,Lysate: 40 ug,Lane 1-7: 293T cells, A431 cells, Hela cells, HepG2 cells, Human fetal liver tissue, PC3 cells, Human placenta tissue,Primary antibody: MBS7130146(VPS26A Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds)
Product Categories/Family for anti-VPS26A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,938 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 26A isoform 2
NCBI Official Synonym Full Names
vacuolar protein sorting 26 homolog A (S. pombe)
NCBI Official Symbol
VPS26A
NCBI Official Synonym Symbols
HB58; PEP8A; VPS26; Hbeta58
NCBI Protein Information
vacuolar protein sorting-associated protein 26A; vesicle protein sorting 26A
UniProt Protein Name
Vacuolar protein sorting-associated protein 26A
UniProt Gene Name
VPS26A
UniProt Synonym Gene Names
VPS26; hVPS26
UniProt Entry Name
VP26A_HUMAN

NCBI Description

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

VPS26A: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Belongs to the VPS26 family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 10q21.1

Cellular Component: intracellular membrane-bound organelle; retromer complex; early endosome; endosome membrane; cytosol; endosome; vesicle

Molecular Function: protein binding; protein transporter activity

Biological Process: intracellular protein transport; retrograde transport, endosome to Golgi

Research Articles on VPS26A

Similar Products

Product Notes

The VPS26A vps26a (Catalog #AAA7130146) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS26A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VPS26A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:500-1:2000 IHC: 1:30-1:150. Researchers should empirically determine the suitability of the VPS26A vps26a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS26A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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