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Testing Data (Sample (30 ug of whole cell lysate) A: Molt-4 7.5% SDS PAGE Primary antibody diluted at 1: 1000)

Rabbit anti-Human VPS16 Polyclonal Antibody | anti-VPS16 antibody

VPS16 antibody

Gene Names
VPS16; hVPS16
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Purified by antigen-affinity chromatography.
Synonyms
VPS16; Polyclonal Antibody; VPS16 antibody; anti-VPS16 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
839
Applicable Applications for anti-VPS16 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide contain a sequence corresponding to a region within amino acids 715 and 774 of human VPS16
Target Name
VPS16
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample (30 ug of whole cell lysate) A: Molt-4 7.5% SDS PAGE Primary antibody diluted at 1: 1000)

Testing Data (Sample (30 ug of whole cell lysate) A: Molt-4 7.5% SDS PAGE Primary antibody diluted at 1: 1000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using VPS16 antibody at 1: 100 dilution.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using VPS16 antibody at 1: 100 dilution.)
Related Product Information for anti-VPS16 antibody
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq]
Product Categories/Family for anti-VPS16 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78,300 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 16 homolog isoform 1
NCBI Official Synonym Full Names
vacuolar protein sorting 16 homolog (S. cerevisiae)
NCBI Official Symbol
VPS16
NCBI Official Synonym Symbols
hVPS16
NCBI Protein Information
vacuolar protein sorting-associated protein 16 homolog
UniProt Protein Name
Vacuolar protein sorting-associated protein 16 homolog
UniProt Gene Name
VPS16
UniProt Synonym Gene Names
hVPS16
UniProt Entry Name
VPS16_HUMAN

NCBI Description

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

Uniprot Description

VPS16: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Belongs to the VPS16 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: recycling endosome; cell soma; lysosomal membrane; lysosome; axon; late endosome membrane; late endosome; early endosome; actin filament

Molecular Function: actin filament binding; actin binding

Biological Process: intracellular protein transport; entry of virus into host cell; regulation of vacuole fusion, non-autophagic; endosome transport

Research Articles on VPS16

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Product Notes

The VPS16 vps16 (Catalog #AAA9404712) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS16 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VPS16 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250. Researchers should empirically determine the suitability of the VPS16 vps16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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