Rabbit anti-Human, Rat VIP Polyclonal Antibody | anti-VIP antibody

VIP Antibody

Cat. Num. AAA7126699

• Gene Names: VIP; PHM27
• Reactivity: Human, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: VIP; Polyclonal Antibody; VIP Antibody; vasoactive intestinal peptide; anti-VIP antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-VIP antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: ELISA: 1:2000-1:5000; IHC: 1:25-1:100
• Immunogen: Full length fusion protein
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126699(VIP Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using MBS7126699(VIP Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))

Product Categories/Family for anti-VIP antibody

Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 4507897
• NCBI GeneID: 7432
• NCBI Accession #: NP_003372.1
• NCBI GenBank Nucleotide #: NM_003381.3
• UniProt Accession #: P01282; Q5TCY8; Q5TCY9; Q96QK3
• Molecular Weight: 19,169 Da
• NCBI Official Full Name: VIP peptides isoform 1 preproprotein
• NCBI Official Synonym Full Names: vasoactive intestinal peptide
• NCBI Official Symbol: VIP
• NCBI Official Synonym Symbols: PHM27
• NCBI Protein Information: VIP peptides; prepro-VIP
• UniProt Protein Name: VIP peptides
• Protein Family: VIP peptides
• UniProt Gene Name: VIP
• UniProt Synonym Gene Names: VIP
• UniProt Entry Name: VIP_HUMAN

NCBI Description

The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

VIP: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. Belongs to the glucagon family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6q25

Cellular Component: cell soma; extracellular region

Molecular Function: neuropeptide hormone activity; protein binding; hormone activity

Biological Process: negative regulation of smooth muscle cell proliferation; mRNA stabilization; negative regulation of potassium ion transport; regulation of signal transduction; positive regulation of vasodilation; body fluid secretion; G-protein coupled receptor protein signaling pathway; regulation of protein localization; learning and/or memory; positive regulation of cell proliferation; positive regulation of protein catabolic process; positive regulation of endothelial cell proliferation; regulation of sensory perception of pain; negative regulation of apoptosis