Rabbit anti-Human VGLUT3 Polyclonal Antibody | anti-SLC17A8 antibody

Anti-VGLUT3 (Vesicular Glutamate Transporter 3, Solute Carrier Family 17 Member 8, SLC17A8)

Cat. Num. AAA624051

• Gene Names: SLC17A8; DFNA25; VGLUT3
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Affinity Purified
• Synonyms: VGLUT3; Polyclonal Antibody; Anti-VGLUT3 (Vesicular Glutamate Transporter 3; Solute Carrier Family 17 Member 8; SLC17A8); Vesicular Glutamate Transporter 3; SLC17A8; anti-SLC17A8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human VGLUT3.
• Purity/Purification: Affinity Purified
• Form/Format: Supplied as a liquid in PBS, 0.1% BSA.
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-SLC17A8 antibody: ELISA; Western Blot; Immunohistochemistry
• Application Notes: Suitable for use in Western Blot, ELISA, and Immunohistochemistry.; Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence); ELISA: 1:100,000; 50-100ng of control peptide/well; Immunohistochemistry: 2-10ug/ml
• Immunogen: Synthetic peptide corresponding to 19aa of human VGLUT3 (Accession #Q8NDX2), C-terminal, cytoplasmic domain (KLH).
• Source Information: Human
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.; Shipping Temperature: Blue Ice

Related Product Information for anti-SLC17A8 antibody

Vesicular glutamate transporter (VGLUT) is responsible for the active transport of L-glutamate in synaptic vesicles and thus plays an essential role in the glutamatergic chemical transmission in the central nervous system. VGLUT comprises three isoforms, VGLUT1, 2, and 3, and is a potential marker for the glutamatergic phenotype. Recent studies indicated that VGLUT is also expressed in non-neuronal cells, and localized with various organelles such as synaptic-like microvesicles in the pineal gland, and hormone- containing secretory granules in endocrine cells. L-Glutamate is stored in these organelles, secreted upon various forms of stimulation, and then acts as a paracrine-like modulator. Thus, VGLUTs highlight a novel framework of glutamatergic signaling and reveal its diverse modes of action.

VGLUT3 expression is restricted to the brain, where it is predominantly located in synaptic vesicles. VGLUT3 shows strong sequence homology (~73%) to Differentiation-associated Na- dependent inorganic phosphate cotransporter. Mouse and rat respectively show 90 and 92% identity with the human VGLUT3 protein sequence.

Product Categories/Family for anti-SLC17A8 antibody

Abs to Transporters

NCBI and Uniprot Product Information

• NCBI GI #: 223718438
• NCBI GeneID: 246213
• NCBI Accession #: NP_001138760.1
• NCBI GenBank Nucleotide #: NM_001145288.1
• UniProt Accession #: Q8NDX2; Q17RQ8; B3KXZ6; B7ZKV4
• Molecular Weight: 64,991 Da
• NCBI Official Full Name: vesicular glutamate transporter 3 isoform 2
• NCBI Official Synonym Full Names: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
• NCBI Official Symbol: SLC17A8
• NCBI Official Synonym Symbols: DFNA25; VGLUT3
• NCBI Protein Information: vesicular glutamate transporter 3; solute carrier family 17 member 8
• UniProt Protein Name: Vesicular glutamate transporter 3
• Protein Family: Vesicular glutamate transporter
• UniProt Gene Name: SLC17A8
• UniProt Synonym Gene Names: VGLUT3
• UniProt Entry Name: VGLU3_HUMAN