Rabbit anti-Rat VGAT Polyclonal Antibody | anti-SLC32A1 antibody
VGAT (solute carrier family 32 (GABA vesicular transporter) member 1, GABA and glycine transporter, SLC32A 1, Solute carrier family 32 member 1, VGAT, VIAAT, Vesicular GABA Amino Acid Transporter, Vesicular GABA transporter, Vesicular inhibitory amino aci
Gene Names
SLC32A1; VGAT; VIAAT
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
SerumSerum
Synonyms
VGAT; Polyclonal Antibody; VGAT (solute carrier family 32 (GABA vesicular transporter) member 1; GABA and glycine transporter; SLC32A 1; Solute carrier family 32 member 1; VIAAT; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino aci; Anti -VGAT (solute carrier family 32 (GABA vesicular transporter) member 1; anti-SLC32A1 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat VGAT. Species Sequence Homology
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied lyophilized powder.
Applicable Applications for anti-SLC32A1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Immunofluorescence, ELISA, Western Blot.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Immunogen
17 amino acid peptide sequence near the carboxy terminal region of rat VGAT (KLH coupled). Cellular Localization: Cytoplasmic
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-SLC32A1 antibody
Classical neurotransmitters are synthesized in the cytoplasm, and so must be transported into synaptic vesicles for regulated exocytosis of vesicles filled with neurotransmitter. Although the vesicular transporters for monoamines and acetylcholine have been identified, the proteins responsible for packaging the primary inhibitory and excitatory transmitters, gamma aminobutyric acid (GABA) and glutamate have only recently been identified. Studies in the nematode Caenorhabditis elegans have implicated the gene unc-47 in the release of GABA. Recently, rat homolog of unc-47 have been cloned and characterized. Rat VGAT, a 525 aa membrane protein with ten transmembrane domains, is expressed by central GABA neurons. Both N and C-termini are predicted to be cytoplasmic. Rat VGAT and unc-47 share ~38% sequence identity. Rat VGAT is primarily expressed in the brain
Product Categories/Family for anti-SLC32A1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,415 Da
NCBI Official Full Name
vesicular inhibitory amino acid transporter
NCBI Official Synonym Full Names
solute carrier family 32 (GABA vesicular transporter), member 1
NCBI Official Symbol
SLC32A1
NCBI Official Synonym Symbols
VGAT; VIAAT
NCBI Protein Information
vesicular inhibitory amino acid transporter; hVIAAT; vesicular GABA transporter; GABA and glycine transporter; solute carrier family 32 member 1
UniProt Protein Name
Vesicular inhibitory amino acid transporter
Protein Family
UniProt Gene Name
SLC32A1
UniProt Synonym Gene Names
VGAT; VIAAT; hVIAAT
UniProt Entry Name
VIAAT_HUMAN
NCBI Description
The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC32A1: Involved in the uptake of GABA and glycine into the synaptic vesicles. Belongs to the amino acid/polyamine transporter 2 family.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 20q11.23
Cellular Component: neuron projection; synaptic vesicle membrane; dendrite; integral to membrane; plasma membrane
Molecular Function: glycine transmembrane transporter activity; gamma-aminobutyric acid:hydrogen symporter activity; amino acid transmembrane transporter activity
Biological Process: glycine transport; synaptic transmission; neurotransmitter secretion; ion transport; transmembrane transport; gamma-aminobutyric acid transport; aging
Research Articles on SLC32A1
Similar Products
Product Notes
The SLC32A1 slc32a1 (Catalog #AAA615406) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VGAT (solute carrier family 32 (GABA vesicular transporter) member 1, GABA and glycine transporter, SLC32A 1, Solute carrier family 32 member 1, VGAT, VIAAT, Vesicular GABA Amino Acid Transporter, Vesicular GABA transporter, Vesicular inhibitory amino aci reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VGAT can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Immunofluorescence, ELISA, Western Blot. Dilution: Western Blot: 1:1000-1:5000 ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well. Researchers should empirically determine the suitability of the SLC32A1 slc32a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VGAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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