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anti-Rat Vasoactive Intestinal Peptide Receptor Gene Repressor Protein Polyclonal Antibody | anti-Rfc1 antibody

Anti - Vasoactive Intestinal Peptide Receptor Gene Repressor Protein (VIPRRP)

Gene Names
Rfc1; Recc1
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
Vasoactive Intestinal Peptide Receptor Gene Repressor Protein; Polyclonal Antibody; Anti - Vasoactive Intestinal Peptide Receptor Gene Repressor Protein (VIPRRP); Vasoactive Intestinal Peptide Receptor Gene Repressor Protein (VIPRRP); anti-Rfc1 antibody
Ordering
For Research Use Only!
Host
Host: Rabbit
Source: Rat
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Control peptide from Rat VIPRRP, C-terminus shows no significant homology with other species.
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, before the addition of glycerol to 40%.
Concentration
~1mg/ml (varies by lot)
Sequence Length
656
Applicable Applications for anti-Rfc1 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA, Western Blotting. Other applications not tested.
Dilution: ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plates at 1ug/ml.
Western Blotting: 1-10ug/ml for affinity pure antibody using ECL technique
Optimal dilutions to be determined by the researcher.
Immunogen
17aa peptide from Rat VIPRRP, C-terminus
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Rfc1 antibody
Vasoactive intestinal peptide (VIP) is a 28-aminoacid peptide (human, chr 6q26-q27). Expressed and secreted by neurons innervating primary and secondary immune organs such as lymph nodes with a Mol.wt of 20kD. VIP is a potent neurotrophic factor causes vasodilation, lowers arterial blood pressure, and relaxes the smooth muscle of trachea, stomach and gall bladder. VIP also modulates several T-lymphocyte activities including motility, cytokine production, proliferation and apoptosis, VIP exerts its biological activity by binding to two closely related class II G-protein-coupled receptors VPAC-1 and VPAC-2 beside this VIP has its own receptors VIPR1&2 (Vasoactive Intestinal Polypeptide Receptor 1&2) and VIPRRP (VIP receptor-gene repressor protein). VIP shows similarities to glucagon, secretin and gastric inhibitory peptide (GIP) as such it has been considered a member of the glucagon-secretin family. The VIP is 100% conserved in mouse, rat and human. VIP is considered to be a viable candidate for the development of treatments for rheumatoid arthritis, since treatment with VIP significantly reduced incidence of severity of arthritis, the therapeutic effect of VIP was associated with downregulation of both inflammatory and autoimmune components of the disease.
Product Categories/Family for anti-Rfc1 antibody
References
• 1. Lin Pei (2000) JBC, 275, 1176-11822. Bodner, M (1985) PNA,82, 3548-35513. Delgado, M (2001) Nature Med, 7, 563-5684. Gotoh, E. (1998) Biochem. Int, 17, 555-562

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
72,972 Da
NCBI Official Full Name
VIP-receptor-gene repressor protein
NCBI Official Synonym Full Names
replication factor C (activator 1) 1
NCBI Official Symbol
Rfc1
NCBI Official Synonym Symbols
Recc1
NCBI Protein Information
replication factor C (activator 1) 1; replication factor C (activator 1) 1; replication factor C 1
UniProt Protein Name
VIP-receptor-gene repressor protein
Protein Family
UniProt Gene Name
Rfc1
UniProt Synonym Gene Names
Recc1
UniProt Entry Name
O88461_RAT

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Product Notes

The Rfc1 rfc1 (Catalog #AAA610519) is an Antibody produced from Host: Rabbit Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti - Vasoactive Intestinal Peptide Receptor Gene Repressor Protein (VIPRRP) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Vasoactive Intestinal Peptide Receptor Gene Repressor Protein can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA, Western Blotting. Other applications not tested. Dilution: ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plates at 1ug/ml. Western Blotting: 1-10ug/ml for affinity pure antibody using ECL technique Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Rfc1 rfc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vasoactive Intestinal Peptide Receptor Gene Repressor Protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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