Rabbit anti-Human, Mouse USP49 Polyclonal Antibody | anti-USP49 antibody

USP49, NT (USP49, Ubiquitin carboxyl-terminal hydrolase 49, Deubiquitinating enzyme 49, Ubiquitin thioesterase 49, Ubiquitin-specific-processing protease 49)

Cat. Num. AAA644552

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: USP49; Polyclonal Antibody; NT (USP49; Ubiquitin carboxyl-terminal hydrolase 49; Deubiquitinating enzyme 49; Ubiquitin thioesterase 49; Ubiquitin-specific-processing protease 49); Anti -USP49; anti-USP49 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-USP49 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: USP49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human USP49.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(USP49 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the USP49 antibody detected the USP49 protein (arrow).)

Western Blot (WB)

(USP49 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the USP49 antibody detected USP49 protein (arrow).)

Product Categories/Family for anti-USP49 antibody

Antibodies; Abs to Ubiquitin

NCBI and Uniprot Product Information

• NCBI GI #: 21361749
• NCBI GeneID: 25862
• NCBI Accession #: NP_061031.2
• NCBI GenBank Nucleotide #: NM_018561.3
• UniProt Accession #: Q70CQ1; Q5T3D9; Q5T3E0; Q96CK4
• Molecular Weight: 79,198 Da
• NCBI Official Full Name: ubiquitin carboxyl-terminal hydrolase 49
• NCBI Official Synonym Full Names: ubiquitin specific peptidase 49
• NCBI Official Symbol: USP49
• NCBI Protein Information: ubiquitin carboxyl-terminal hydrolase 49; ubiquitin thioesterase 49; deubiquitinating enzyme 49; ubiquitin thiolesterase 49; ubiquitin specific protease 49; ubiquitin-specific-processing protease 49
• UniProt Protein Name: Ubiquitin carboxyl-terminal hydrolase 49
• Protein Family: Ubiquitin carboxyl-terminal hydrolase
• UniProt Gene Name: USP49
• UniProt Entry Name: UBP49_HUMAN

Uniprot Description

USP49: Belongs to the peptidase C19 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.19.12; Ubiquitin-specific protease; Protease

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: nucleus

Molecular Function: protein binding; zinc ion binding; histone binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity

Biological Process: nuclear mRNA splicing, via spliceosome; proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination