Rabbit anti-Human UQCC2 Polyclonal Antibody | anti-UQCC2 antibody

UQCC2 Antibody

Cat. Num. AAA7045800

• Gene Names: UQCC2; M19; Cbp6; MNF1; C6orf125; bA6B20.2
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: UQCC2; Polyclonal Antibody; UQCC2 Antibody; Ubiquinol-cytochrome-c reductase complex assembly factor 2; Breast cancer-associated protein SGA-81M; Mitochondrial nucleoid factor 1; Mitochondrial protein M19; C6orf125; MNF1; anti-UQCC2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 126

• Applicable Applications for anti-UQCC2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Species: Human
• Immunogen: Recombinant human Ubiquinol-cytochrome-c reductase complex assembly factor 2 protein (C-113AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: UQCC2 antibody at 1.74 ug/mlLane 1: 293T whole cell lysateLane 2: A431 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 15 kDaObserved band size: 15,25 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7045800 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7045800 at dilution of 1:100)

Related Product Information for anti-UQCC2 antibody

Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability.

NCBI and Uniprot Product Information

• NCBI GI #: 14150128
• NCBI GeneID: 84300
• NCBI Accession #: NP_115716.1
• NCBI GenBank Nucleotide #: NM_032340.3
• UniProt Accession #: Q9BRT2; B2R4I0
• Molecular Weight: 14,875 Da
• NCBI Official Full Name: ubiquinol-cytochrome-c reductase complex assembly factor 2
• NCBI Official Synonym Full Names: ubiquinol-cytochrome c reductase complex assembly factor 2
• NCBI Official Symbol: UQCC2
• NCBI Official Synonym Symbols: M19; Cbp6; MNF1; C6orf125; bA6B20.2
• NCBI Protein Information: ubiquinol-cytochrome-c reductase complex assembly factor 2
• UniProt Protein Name: Ubiquinol-cytochrome-c reductase complex assembly factor 2
• Protein Family: Ubiquinol-cytochrome-c reductase complex assembly factor
• UniProt Gene Name: UQCC2
• UniProt Synonym Gene Names: C6orf125; MNF1
• UniProt Entry Name: UQCC2_HUMAN

NCBI Description

This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]

Uniprot Description

UQCC2: Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nucleus

Molecular Function: protein binding

Biological Process: regulation of insulin secretion; regulation of oxidative phosphorylation

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 7