Immunohistochemistry (IHC)
(Immunohistochemical staining of paraffin-embedded MCF7 xenograft using UNC13B antibody at a dilution of 1:500)
Rabbit UNC13B Polyclonal Antibody | anti-UNC13B antibody
UNC13B Antibody
Gene Names
UNC13B; UNC13; MUNC13; Unc13h2; munc13-2
Applications
Immunohistochemistry, Western Blot
Purity
Antigen-Affinity Chromatography
Synonyms
UNC13B; Polyclonal Antibody; UNC13B Antibody; Affinity Purified Rabbit Polyclonal UNC13B Antibody; Polyclonal UNC13B antibody; Anti-UNC13B antibody; MUNC13 antibody; UNCB 13 antibody; UNC13B antibody; UNCB 13; hmunc13 antibody; homolog of rat Munc13 (diacylglycerol-binding) antibody; MGC133279 antibody; Unc13h2 antibody; munc13-2 antibody; UNCB-13; UNC13 antibody; UNCB-13 antibody; MGC133280 antibody; anti-UNC13B antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen-Affinity Chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1197
Applicable Applications for anti-UNC13B antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100-1:500
WB: 1:1000-1:10000
WB: 1:1000-1:10000
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical staining of paraffin-embedded MCF7 xenograft using UNC13B antibody at a dilution of 1:500)
Immunohistochemistry (IHC)
(Immunohistochemical staining of paraffin-embedded MCF7 xenograft using UNC13B antibody at a dilution of 1:500)
Western Blot (WB)
(Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 5% SDS PAGE gel and UNC13B antibody at a dilution of 1:5000)
Western Blot (WB)
(Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 5% SDS PAGE gel and UNC13B antibody at a dilution of 1:5000)
Related Product Information for anti-UNC13B antibody
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Product Categories/Family for anti-UNC13B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
181 kDa
NCBI Official Full Name
UNC13B protein
NCBI Official Synonym Full Names
unc-13 homolog B
NCBI Official Symbol
UNC13B
NCBI Official Synonym Symbols
UNC13; MUNC13; Unc13h2; munc13-2
NCBI Protein Information
protein unc-13 homolog B
Protein Family
NCBI Description
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Research Articles on UNC13B
Similar Products
Product Notes
The UNC13B (Catalog #AAA5312346) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's UNC13B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100-1:500 WB: 1:1000-1:10000. Researchers should empirically determine the suitability of the UNC13B for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UNC13B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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