Rabbit anti-Human UDB17 Polyclonal Antibody | anti-UDB17 antibody

UDB17, ID (UDP-glucuronosyltransferase 2B17, UDPGT 2B17, C19-steroid-specific UDP-glucuronosyltransferase, C19-steroid-specific UDPGT, UGT2B17) (MaxLight 750)

Cat. Num. AAA6504351

• Gene Names: UGT2B17; BMND12; UDPGT2B17
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Ammonium Sulfate Precipitation
• Synonyms: UDB17; Polyclonal Antibody; ID (UDP-glucuronosyltransferase 2B17; UDPGT 2B17; C19-steroid-specific UDP-glucuronosyltransferase; C19-steroid-specific UDPGT; UGT2B17) (MaxLight 750); anti-UDB17 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human UDB17
• Purity/Purification: Purified by Ammonium Sulfate Precipitation
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
• Sequence Length: 530

• Applicable Applications for anti-UDB17 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:50-1:100; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide corresponding to a portion of amino acids within aa121-150 in the center region of human UDB17
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of UDB17 antibody (Center) in Y79 cell line lysates (35ug/lane). UDB17 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(UDB17 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human Prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UDB17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Product Categories/Family for anti-UDB17 antibody

Antibodies; Enzymes; Glycosyltransferase

References

1. Balliet, R.M., Cancer Res. 69(7), 2981-2989 (2009). 2. Juul, A., J. Clin. Endocrinol. Metab. 94(3), 1005-1011 (2009).

NCBI and Uniprot Product Information

• NCBI GI #: 4507821
• NCBI GeneID: 7367
• NCBI Accession #: NP_001068
• NCBI GenBank Nucleotide #: NP_001068.1
• UniProt Accession #: O75795
• Molecular Weight: 61.095
• NCBI Official Full Name: UDP-glucuronosyltransferase 2B17
• NCBI Official Synonym Full Names: UDP glucuronosyltransferase family 2 member B17
• NCBI Official Symbol: UGT2B17
• NCBI Official Synonym Symbols: BMND12; UDPGT2B17
• NCBI Protein Information: UDP-glucuronosyltransferase 2B17
• UniProt Protein Name: UDP-glucuronosyltransferase 2B17
• UniProt Gene Name: UGT2B17
• UniProt Synonym Gene Names: UDPGT 2B17; C19-steroid-specific UDPGT
• UniProt Entry Name: UDB17_HUMAN

NCBI Description

This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]