Rabbit anti-Human UCK1 Polyclonal Antibody | anti-UCK1 antibody

UCK1 Antibody

Cat. Num. AAA9402117

• Gene Names: UCK1; URK1
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: UCK1; Polyclonal Antibody; UCK1 Antibody; URK1; RP11-334J6.5; anti-UCK1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total UCK1 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2.1 mg/ml (varies by lot)
• Sequence Length: 201

• Applicable Applications for anti-UCK1 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:50-1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Full length fusion protein
• Target Name: UCK1
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/50.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/50.)

Related Product Information for anti-UCK1 antibody

This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms.

Product Categories/Family for anti-UCK1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 209863022
• NCBI GeneID: 83549
• NCBI Accession #: NP_001129426.1
• NCBI GenBank Nucleotide #: NM_001135954.1
• UniProt Accession #: Q9HA47; Q5JT09; Q5JT10; Q5JT12; Q5JT13; Q6IA74; Q96BJ0
• Molecular Weight: 32,275 Da
• NCBI Official Full Name: uridine-cytidine kinase 1 isoform b
• NCBI Official Synonym Full Names: uridine-cytidine kinase 1
• NCBI Official Symbol: UCK1
• NCBI Official Synonym Symbols: URK1
• NCBI Protein Information: uridine-cytidine kinase 1
• UniProt Protein Name: Uridine-cytidine kinase 1
• Protein Family: Uridine-cytidine kinase
• UniProt Gene Name: UCK1
• UniProt Synonym Gene Names: URK1; UCK 1
• UniProt Entry Name: UCK1_HUMAN

NCBI Description

This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]

Uniprot Description

UCK1: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine. Belongs to the uridine kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.1.48; Nucleotide Metabolism - pyrimidine; Kinase, other; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 9q34.13

Cellular Component: cytosol

Molecular Function: nucleoside kinase activity; uridine kinase activity; ATP binding

Biological Process: pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; pyrimidine nucleoside salvage; phosphorylation