Rabbit anti-Human UBXN8 Polyclonal Antibody | anti-UBXN8 antibody

UBXN8, NT (UBXN8, D8S2298E, REP8, UBXD6, UBX domain-containing protein 8, Reproduction 8 protein, UBX domain-containing protein 6) (FITC)

Cat. Num. AAA6361050

• Gene Names: UBXN8; REP8; UBXD6; D8S2298E
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: UBXN8; Polyclonal Antibody; NT (UBXN8; D8S2298E; REP8; UBXD6; UBX domain-containing protein 8; Reproduction 8 protein; UBX domain-containing protein 6) (FITC); UBX domain-containing protein 6; anti-UBXN8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-UBXN8 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: UBXN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human UBXN8.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(UBXN8 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the UBXN8 antibody detected the UBXN8 protein (arrow).)

Product Categories/Family for anti-UBXN8 antibody

Antibodies; Proteins

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Yamabe, Y., et al. Genomics 39(2):198-204(1997).

NCBI and Uniprot Product Information

• NCBI GI #: 5031651
• NCBI GeneID: 7993
• NCBI Accession #: NP_005662.1
• NCBI GenBank Nucleotide #: NM_005671.2
• UniProt Accession #: O00124; Q7Z6F2
• Molecular Weight: 30,541 Da
• NCBI Official Full Name: UBX domain-containing protein 8
• NCBI Official Synonym Full Names: UBX domain protein 8
• NCBI Official Symbol: UBXN8
• NCBI Official Synonym Symbols: REP8; UBXD6; D8S2298E
• NCBI Protein Information: UBX domain-containing protein 8; rep-8 protein; reproduction 8 protein; UBX domain containing 6; Reproduction/chromosome 8; UBX domain-containing protein 6
• UniProt Protein Name: UBX domain-containing protein 8
• Protein Family: UBX domain-containing protein
• UniProt Gene Name: UBXN8
• UniProt Synonym Gene Names: D8S2298E; REP8; UBXD6; Rep-8 protein
• UniProt Entry Name: UBXN8_HUMAN

NCBI Description

p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2013]