Rabbit anti-Human UBL4A Polyclonal Antibody | anti-UBL4A antibody

UBL4A Rabbit pAb

Cat. Num. AAA4754525

• Gene Names: UBL4A; GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E; DXS254E
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: UBL4A; Polyclonal Antibody; UBL4A Rabbit pAb; GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E; DXS254E; anti-UBL4A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-UBL4A antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:1000-1:5000
• Immunogen: Full length fusion protein
• Conjugation: Unconjugated
• Molecular Function: UBL4A, also known as GDX, has been characterized as a ubiquitously expressed and highly conserved protein from humans to plants. The N-terminal region of UBL4A shares 43% sequence identity with ubiquitin, however the C-terminal region has no homology to ubiquitin and it is therefore unlikely that UBL4A plays any role in targeting cellular proteins for degradation.
• Modification: Unmodified
• Cell Position: Cytoplasm, Nucleus
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-6: Hepg2 and Jurkat cell, human fetal brain tissue and hela cell, A431 and PC3 cell, Primary antibody: 123469(UBL4A Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 123469(UBL4A Antibody) at dilution 1/40. (Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 123469(UBL4A Antibody) at dilution 1/40. (Original magnification: ×200))

Product Categories/Family for anti-UBL4A antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 34783505
• NCBI GeneID: 8266
• UniProt Accession #: P11441; Q5HY80
• Molecular Weight: 17,777 Da
• NCBI Official Full Name: Homo sapiens ubiquitin-like 4A, mRNA
• NCBI Official Synonym Full Names: ubiquitin like 4A
• NCBI Official Symbol: UBL4A
• NCBI Official Synonym Symbols: GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E; DXS254E
• NCBI Protein Information: ubiquitin-like protein 4A
• UniProt Protein Name: Ubiquitin-like protein 4A
• Protein Family: Ubiquitin-like protein
• UniProt Gene Name: UBL4A
• UniProt Synonym Gene Names: DXS254E; GDX; UBL4
• UniProt Entry Name: UBL4A_HUMAN

Uniprot Description

UBL4A: Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.

Protein type: Ubiquitin-like modifier

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytosol

Molecular Function: protein binding; small conjugating protein ligase activity

Biological Process: transport; protein modification process