Western Blot (WB)
(UBE2J1 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the UBE2J1 antibody detected the UBE2J1 protein (arrow).)
Rabbit UBE2J1 Polyclonal Antibody | anti-UBE2J1 antibody
UBE2J1 Antibody (N-term)
Western Blot (WB)
(UBE2J1 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the UBE2J1 antibody detected the UBE2J1 protein (arrow).)
Western Blot (WB)
(UBE2J1 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the UBE2J1 antibody detected the UBE2J1 protein (arrow).)
important cellular mechanism for targeting abnormal or short-lived
proteins for degradation. Ubiquitination involves at least three
classes of enzymes: ubiquitin-activating enzymes, or E1s,
ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein
ligases, or E3s. This gene encodes a member of the E2
ubiquitin-conjugating enzyme family. This enzyme is located in the
membrane of the endoplasmic reticulum (ER) and may contribute to
quality control ER-associated degradation by the
ubiquitin-proteasome system.
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Oh, R.S., et al. J. Biol. Chem. 281(30):21480-21490(2006)
Wu, C.J., et al. EMBO J. 24(10):1886-1898(2005)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
NCBI and Uniprot Product Information
NCBI Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]
Uniprot Description
UBE2J1: Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). Belongs to the ubiquitin-conjugating enzyme family.
Protein type: Ligase; EC 6.3.2.19; Ubiquitin ligase; Ubiquitin conjugating system; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: endoplasmic reticulum membrane; cytoplasm; integral to membrane
Molecular Function: small conjugating protein ligase activity; ubiquitin protein ligase binding; ATP binding; ligase activity
Biological Process: ER-associated protein catabolic process; protein ubiquitination; protein amino acid N-linked glycosylation via asparagine
Research Articles on UBE2J1
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Product Notes
The UBE2J1 ube2j1 (Catalog #AAA9203114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The UBE2J1 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's UBE2J1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the UBE2J1 ube2j1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UBE2J1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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