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Immunofluorescence (IF) (Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase (Phospho-Ser19) antibody (Red).)

Rabbit Tyrosine Hydroxylase Polyclonal Antibody | anti-TYH antibody

Tyrosine Hydroxylase Antibody (Ser19)

Gene Names
TH; TYH; DYT14; DYT5b
Applications
Immunofluorescence
Purity
Affinity Chromatography
Synonyms
Tyrosine Hydroxylase; Polyclonal Antibody; Tyrosine Hydroxylase Antibody (Ser19); Rabbit Polyclonal Tyrosine Hydroxylase Antibody (Ser19); Polyclonal Tyrosine Hydroxylase antibody; Anti-Tyrosine Hydroxylase antibody; Tyrosine 3-hydroxylase antibody; Tyrosine 3-monooxygenase antibody; tyrosine hydroxylase antibody; dystonia 14 antibody; DYT14 antibody; DYT5b antibody; HTH-2 antibody; TH antibody; TH2 antibody; TY3H antibody; TYH antibody; anti-TYH antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
Tyrosine Hydroxylase antibody (Ser19) detects endogenous levels of TyrosineHydroxylase only when phosphorylated at serine19
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
106
Applicable Applications for anti-TYH antibody
Immunofluorescence (IF)
Application Notes
IF: 1:100-1:200
Immunogen
Tyrosine Hydroxylase antibody was raised in Rabbit using a synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine19(A-V-SP-E-Q) as the immunogen.
Cross-Reactivity
Rat
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.

Immunofluorescence (IF)

(Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase (Phospho-Ser19) antibody (Red).)

Immunofluorescence (IF) (Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase (Phospho-Ser19) antibody (Red).)
Related Product Information for anti-TYH antibody
Tyrosine Hydroxylase is an oxygenase which means it uses molecular oxygen to hydroxylate its substrates. One of the oxygen atoms in O2 is used to hydroxylate the tyrosine molecule to obtain L-DOPA and the other one is used to hydroxylate the cofactor. Like the other aromatic amino acid hydroxylases (AAAHs), tyrosine hydroxylase use the cofactor tetrahydrobiopterin (BH4) under normal conditions, although other similar molecules may also work as a cofactor for tyrosine hydroxylase.
Product Categories/Family for anti-TYH antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
tyrosine hydroxylase, partial
NCBI Official Synonym Full Names
tyrosine hydroxylase
NCBI Official Symbol
TH
NCBI Official Synonym Symbols
TYH; DYT14; DYT5b
NCBI Protein Information
tyrosine 3-monooxygenase

NCBI Description

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Research Articles on TYH

Similar Products

Product Notes

The TYH (Catalog #AAA5313729) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Tyrosine Hydroxylase can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:100-1:200. Researchers should empirically determine the suitability of the TYH for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tyrosine Hydroxylase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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