Western Blot (WB)
(WB Suggested Anti-TYK2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate)
Rabbit TYK2 Polyclonal Antibody | anti-TYK2 antibody
TYK2 antibody - C-terminal region
Gene Names
TYK2; JTK1; IMD35
Reactivity
Tested Species Reactivity: HumanPredicted Species Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
TYK2; Polyclonal Antibody; TYK2 antibody - C-terminal region; anti-TYK2 antibody
Host
Rabbit
Reactivity
Tested Species Reactivity: Human
Predicted Species Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Predicted Species Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
0.5mg/mL (varies by lot)
Applicable Applications for anti-TYK2 antibody
Western Blot (WB)
Protein Size (# AA)
1187 amino acids
Peptide Sequence
Synthetic peptide located within the following region: HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP
Protein Interactions
KHDRBS2; KRT40; TRAF4; HNRNPK; FHL3; COPS5; JAK3; UBC; HSP90AA1; TYK2; PTAFR; EIF2AK2; LNX1; KLF10; SOCS1; TK1; DNM2; IFNAR1; JAKMIP1; XRCC5; STAM2; PRMT5; IFNAR2; CRKL; GHR; IRS2; IL6ST; STAT2; STAT1; IL13RA1; GNB2L1; PTPN1; PTPN6; PDGFRB; PLAUR; PIK3R1
Tissue Tool
Find tissues and cell lines supported by DNA array analysis to express TYK2.
Blocking Peptide
For anti-TYK2 (MBS3200217) antibody is Catalog # MBS3224950
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TYK2
Predicted Homology Based on Immunogen Sequence
Cow: 91%; Dog: 100%; Guinea Pig: 91%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Replacement Item
This antibody may replace item sc-166686 from Santa Cruz Biotechnology.
Preparation and Storage
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-TYK2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate)
Western Blot (WB)
(WB Suggested Anti-TYK2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: COLO205 cell lysate)
Related Product Information for anti-TYK2 antibody
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Product Categories/Family for anti-TYK2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
134kDa
NCBI Official Full Name
non-receptor tyrosine-protein kinase TYK2
NCBI Official Synonym Full Names
tyrosine kinase 2
NCBI Official Symbol
TYK2
NCBI Official Synonym Symbols
JTK1; IMD35
NCBI Protein Information
non-receptor tyrosine-protein kinase TYK2
UniProt Protein Name
Non-receptor tyrosine-protein kinase TYK2
Protein Family
UniProt Gene Name
TYK2
UniProt Entry Name
TYK2_HUMAN
NCBI Description
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Research Articles on TYK2
Similar Products
Product Notes
The TYK2 tyk2 (Catalog #AAA3200217) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TYK2 antibody - C-terminal region reacts with Tested Species Reactivity: Human Predicted Species Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TYK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TYK2 tyk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TYK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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