Western Blot (WB)
(Western Blot analysis of extracts of mouse liver, using TXNL4B Antibody.)
Rabbit TXNL4B Polyclonal Antibody | anti-TXNL4B antibody
TXNL4B Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
TXNL4B; Polyclonal Antibody; TXNL4B Polyclonal Antibody; Thioredoxin-like protein 4B; Dim1-like protein; DIM2; DLP; anti-TXNL4B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TXNL4B polyclonal antibody detects endogenous levels of TXNL4B protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
149
Applicable Applications for anti-TXNL4B antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant full length Human TXNL4B.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of mouse liver, using TXNL4B Antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of mouse liver, using TXNL4B Antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of A549 cell using TXNL4B antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of A549 cell using TXNL4B antibody.)
Related Product Information for anti-TXNL4B antibody
Dim2, also known as TXNL4B (thioredoxin-like 4B), or DLP, is a 149 amino acid nuclear protein that exists as a homodimer and plays an essential role in pre-mRNA splicing. Evolutionarily related and sharing 38% sequence identity with Dim1, Dim2 is required for S/G(2) transition during the cell cycle and is able to bind the PRP6 (U5-102K) subunit of the spliceosome. The gene encoding Dim2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 17kDa
NCBI Official Full Name
thioredoxin-like protein 4B isoform 1
UniProt Protein Name
Thioredoxin-like protein 4B
Protein Family
UniProt Gene Name
TXNL4B
UniProt Synonym Gene Names
DIM2; DLP
UniProt Entry Name
TXN4B_HUMAN
Uniprot Description
TXNL4B: Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition. Belongs to the DIM1 family.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 16q22.2
Cellular Component: spliceosome; U4/U6 x U5 tri-snRNP complex; snRNP U5
Biological Process: mitosis; spliceosome assembly
Similar Products
Product Notes
The TXNL4B txnl4b (Catalog #AAA3011957) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TXNL4B Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TXNL4B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:200. Researchers should empirically determine the suitability of the TXNL4B txnl4b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNL4B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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