Western Blot
(Western BlotSample: Recombinant TWSG1, Human.)
Rabbit anti-Human Twisted Gastrulation Protein Homolog 1 Polyclonal Antibody | anti-TWSG1 antibody
Polyclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot
(Western BlotSample: Recombinant TWSG1, Human.)
Western Blot
(Western BlotSample: Recombinant TWSG1, Human.)
Western Blot (WB)
(Western BlotSample: Human UrinePrimary Ab: 1ug/ml Rabbit Anti-Human TWSG1 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047))
Western Blot (WB)
(Western BlotSample: Human UrinePrimary Ab: 1ug/ml Rabbit Anti-Human TWSG1 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-PSamples: Human Cerebrum TissuePrimary Ab: 20ug/ml Rabbit Anti-Human TWSG1 AntibodySecond Ab: 2ug/mL HRPLinked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-PSamples: Human Cerebrum TissuePrimary Ab: 20ug/ml Rabbit Anti-Human TWSG1 AntibodySecond Ab: 2ug/mL HRPLinked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047))
NCBI and Uniprot Product Information
Uniprot Description
TWSG1: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development. Belongs to the twisted gastrulation protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 18p11.22
Molecular Function: protein binding; transforming growth factor beta binding
Biological Process: BMP signaling pathway; camera-type eye development; cell differentiation; forebrain development; hemopoiesis; mesoderm formation; negative regulation of BMP signaling pathway; negative regulation of cytokine production; negative regulation of osteoblast differentiation; ossification; positive regulation of BMP signaling pathway; salivary gland morphogenesis; transforming growth factor beta receptor signaling pathway
Research Articles on TWSG1
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Product Notes
The TWSG1 twsg1 (Catalog #AAA2027999) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Twisted Gastrulation Protein Homolog 1 (TWSG1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Twisted Gastrulation Protein Homolog 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipiation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the TWSG1 twsg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Twisted Gastrulation Protein Homolog 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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