Rabbit anti-Human, Mouse TWF2 Polyclonal Antibody | anti-TWF2 antibody
TWF2 Antibody
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
TWF2; Polyclonal Antibody; TWF2 Antibody; A6 related protein; A6-related protein; A6r; A6RP; hA6RP; MSTP011; Protein tyrosine kinase 9 like; Protein tyrosine kinase 9-like; PTK 9L; PTK9L; PTK9L protein tyrosine kinase 9 like; TWF 2; Twf2; TWF2_HUMAN; Twinfilin 1 like protein; Twinfilin 2; Twinfilin actin binding protein homolog 2; Twinfilin like protein; Twinfilin-1-like protein; Twinfilin-2; Twinfilin2; anti-TWF2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
TWF2 Antibody detects endogenous levels of TWF2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TWF2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human TWF2.
Conjugation
Unconjugated
Similarity
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
Post Translational Modifications
In vitro, phosphorylated by PRKCZ, CK2 and SRC.
Subunit Structure
Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF1 and phosphoinositides, PI(4, 5)P2. When bound to PI(4, 5)P2, it is down-regulated. Interacts with MYO7A (By similarity).
Tissue Specificity
Ubiquitously expressed (at protein level).
Function
Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity).
Note
Perinuclear and G-actin-rich cortical actin structure sublocalization.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-TWF2 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The TWF2 twf2 (Catalog #AAA9630710) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TWF2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TWF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TWF2 twf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TWF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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