tumor suppressor candidate 4 Polyclonal Antibody | anti-NPRL2 antibody
Rabbit anti-human tumor suppressor candidate 4 polyclonal Antibody
Gene Names
NPRL2; NPR2; NPR2L; TUSC4
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
Antigen Affinity Purified
Synonyms
tumor suppressor candidate 4; Polyclonal Antibody; Rabbit anti-human tumor suppressor candidate 4 polyclonal Antibody; anti-NPRL2 antibody
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
380
Applicable Applications for anti-NPRL2 antibody
ELISA (EIA)
Immunogen
Human NPR2L,TUSC4
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54487 / sc-54638 / sc-292095
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
23,150 Da
NCBI Official Full Name
Tumor suppressor candidate 4
NCBI Official Synonym Full Names
nitrogen permease regulator-like 2 (S. cerevisiae)
NCBI Official Symbol
NPRL2
NCBI Official Synonym Symbols
NPR2; NPR2L; TUSC4
NCBI Protein Information
nitrogen permease regulator 2-like protein; G21 protein; 2810446G01Rik; gene 21 protein; NPR2-like protein; tumor suppressor candidate 4; homologous to yeast nitrogen permease (candidate tumor suppressor)
UniProt Protein Name
Nitrogen permease regulator 2-like protein
Protein Family
UniProt Gene Name
NPRL2
UniProt Synonym Gene Names
TUSC4; NPR2-like protein; G21 protein
UniProt Entry Name
NPRL2_HUMAN
Uniprot Description
NPRL2: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs. Belongs to the NPR2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Inhibitor; Tumor suppressor
Chromosomal Location of Human Ortholog: 3p21.3
Molecular Function: protein binding; GTPase activator activity; protein kinase activity
Biological Process: negative regulation of kinase activity; protein amino acid phosphorylation; positive regulation of GTPase activity
Research Articles on NPRL2
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Product Notes
The NPRL2 nprl2 (Catalog #AAA711750) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human tumor suppressor candidate 4 polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's tumor suppressor candidate 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the NPRL2 nprl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "tumor suppressor candidate 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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