Rabbit anti-Human TULP3 Polyclonal Antibody | anti-TULP3 antibody

TULP3, CT (TULP3, TUBL3, Tubby-related protein 3, Tubby-like protein 3) (Azide free) (HRP)

Cat. Num. AAA6360303

• Gene Names: TULP3; TUBL3
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TULP3; Polyclonal Antibody; CT (TULP3; TUBL3; Tubby-related protein 3; Tubby-like protein 3) (Azide free) (HRP); Tubby-like protein 3; anti-TULP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-TULP3 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TULP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-400 amino acids from the C-terminal region of human TULP3.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TULP3 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TULP3 antibody detected the TULP3 protein (arrow).)

Related Product Information for anti-TULP3 antibody

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Product Categories/Family for anti-TULP3 antibody

Antibodies; Transcription Factors

References

Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010): Ikeda, A., et al. J. Cell. Sci. 115 (PT 1), 9-14 (2002): Santagata, S., et al. Science 292(5524):2041-2050(2001). Ikeda, S., et al. Invest. Ophthalmol. Vis. Sci. 40(11):2706-2712(1999). Nishina, P.M., et al. Genomics 54(2):215-220(1998).

NCBI and Uniprot Product Information

• NCBI GI #: 238550202
• NCBI GeneID: 7289
• NCBI Accession #: NP_001153880.1
• NCBI GenBank Nucleotide #: NM_001160408.1
• UniProt Accession #: O75386; Q8N5B0; B3KNB7; D3DUQ4
• Molecular Weight: 49,642 Da
• NCBI Official Full Name: tubby-related protein 3 isoform 2
• NCBI Official Synonym Full Names: tubby like protein 3
• NCBI Official Symbol: TULP3
• NCBI Official Synonym Symbols: TUBL3
• NCBI Protein Information: tubby-related protein 3; tubby-like protein 3
• UniProt Protein Name: Tubby-related protein 3
• Protein Family: Tubby-related protein
• UniProt Gene Name: TULP3
• UniProt Synonym Gene Names: TUBL3
• UniProt Entry Name: TULP3_HUMAN

NCBI Description

This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009]