Western Blot (WB)
(Western blot analysis of TSPAN7 Antibody (Center) in CEM cell line lysates (35ug/lane). TSPAN7 (arrow) was detected using the purified Pab.)
Rabbit TSPAN7 Polyclonal Antibody | anti-TSPAN7 antibody
TSPAN7 Antibody (Center)
Predicted Reactivity: Mouse
Predicted Reactivity: Mouse
FC~~1:10~50
Western Blot (WB)
(Western blot analysis of TSPAN7 Antibody (Center) in CEM cell line lysates (35ug/lane). TSPAN7 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of TSPAN7 Antibody (Center) in CEM cell line lysates (35ug/lane). TSPAN7 (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(TSPAN7 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(TSPAN7 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009)
Noor, A., et al. Psychiatr. Genet. 19(3):154-155(2009)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
Uniprot Description
TSPAN7: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Defects in TSPAN7 are the cause of mental retardation X- linked type 58 (MRX58). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xp11.4
Cellular Component: integral to plasma membrane
Biological Process: viral reproduction
Disease: Mental Retardation, X-linked 58
Research Articles on TSPAN7
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Product Notes
The TSPAN7 tspan7 (Catalog #AAA9206828) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 98-124. The TSPAN7 Antibody (Center) reacts with Human Predicted Reactivity: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSPAN7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000 FC~~1:10~50. Researchers should empirically determine the suitability of the TSPAN7 tspan7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSPAN7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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