Sheep TRYPTOPHAN HYDROXYLASE Polyclonal Antibody | anti-TPH1 antibody
SHEEP ANTI RABBIT TRYPTOPHAN HYDROXYLASE
Gene Names
TPH1; TPH2
Reactivity
Human, Mammals (Expected from Sequence), Rat
Applications
Immunohistochemistry, Western Blot
Synonyms
TRYPTOPHAN HYDROXYLASE; Polyclonal Antibody; SHEEP ANTI RABBIT TRYPTOPHAN HYDROXYLASE; anti-TPH1 antibody
Host
Sheep
Reactivity
Human, Mammals (Expected from Sequence), Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
This item recognises tryptophan hydroxylase, an ensyme involved in the synthesis of the neurotransmitter serotonin. In a Western blot Rat pineal, hypothalamus and dorsal raphe tissue have been used. A band at approximately 55 kD is observed.
Form/Format
Purified
Purified Ig - liquid
Purified Ig - liquid
Sequence Length
444
Applicable Applications for anti-TPH1 antibody
Immunohistology Frozen, Western Blot (WB)
Application Notes
Immunohistology: This item has been used for immunohistochemistry on formaldehyde fixed tissue, it is useful for cell body but not fiber staining
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
50% Glycerol
0.01% Bovine Serum Albumin
Preparation
50% Glycerol
0.01% Bovine Serum Albumin
Preparation
Immunogen
Recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E Coli and purified by preparative SDS-PAGE.
Buffer Solution
Buffer Solution
Target Species
Rabbit
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-TPH1 antibody
MBS221196 recognises tryptophan hydroxylase, an ensyme involved in the synthesis of the neurotransmitter serotonin. In a Western blot Rat pineal, hypothalamus and dorsal raphe tissue have been used. A band at approximately 55 kD is observed.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,118 Da
NCBI Official Full Name
tryptophan 5-hydroxylase 1
NCBI Official Symbol
TPH1
NCBI Official Synonym Symbols
TPH2
NCBI Protein Information
tryptophan 5-hydroxylase 1; tryptophan hydroxylase 2
UniProt Protein Name
Tryptophan 5-hydroxylase 1
Protein Family
UniProt Gene Name
TPH1
UniProt Synonym Gene Names
TPH
UniProt Entry Name
TPH1_RABIT
Uniprot Description
TPH1: an enzyme that is rate-limiting in the biosynthesis of serotonin. It catalyzes the biopterin dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Its expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells. Two alternatively spliced isoforms have been described.
Protein type: EC 1.14.16.4; Amino Acid Metabolism - tryptophan; Oxidoreductase
Similar Products
Product Notes
The TPH1 tph1 (Catalog #AAA221196) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The SHEEP ANTI RABBIT TRYPTOPHAN HYDROXYLASE reacts with Human, Mammals (Expected from Sequence), Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TRYPTOPHAN HYDROXYLASE can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Western Blot (WB). Immunohistology: This item has been used for immunohistochemistry on formaldehyde fixed tissue, it is useful for cell body but not fiber staining. Researchers should empirically determine the suitability of the TPH1 tph1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRYPTOPHAN HYDROXYLASE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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