Rabbit anti-Human, Mouse TRIM71 Polyclonal Antibody | anti-TRIM71 antibody
TRIM71 Conjugated Antibody
Gene Names
TRIM71; LIN41; LIN-41
Reactivity
Human, Mouse
Applications
Most Applications
Synonyms
TRIM71; Polyclonal Antibody; TRIM71 Conjugated Antibody; LIN41; LIN-41; anti-TRIM71 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TRIM71 protein.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-TRIM71 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Synthetic peptide of human TRIM71
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-TRIM71 antibody
LIN-41, also called tripartite motif-containing 71 (TRIM71), which was first identified in Caenorhabditis elegans, is responsible for the timing of cell fate determination. By encoding microRNAs (miRNAs), the heterochronic genes let-7 and lin-4 downregulate the gene encoding LIN-41. The miRNAs bind to six complementary sites on the 3' untranslated region (UTR) of the LIN-41 gene. This downregulation positively regulates the timing of the expression of LIN-29, an adult specification transcription factor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
93,385 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM71
NCBI Official Synonym Full Names
tripartite motif containing 71, E3 ubiquitin protein ligase
NCBI Official Symbol
TRIM71
NCBI Official Synonym Symbols
LIN41; LIN-41
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM71; protein lin-41 homolog; abnormal cell LINeage LIN-41; homolog of C. elegans Lin-41; tripartite motif-containing 71; tripartite motif-containing protein 71
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM71
Protein Family
UniProt Gene Name
TRIM71
UniProt Synonym Gene Names
LIN41
UniProt Entry Name
LIN41_HUMAN
Uniprot Description
TRIM71: May be involved in controlling the timing of organ formation during development. Belongs to the TRIM/RBCC family.
Chromosomal Location of Human Ortholog: 3p22.3
Molecular Function: miRNA binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: neural tube development; protein autoubiquitination; fibroblast growth factor receptor signaling pathway; neural tube closure; miRNA-mediated gene silencing, negative regulation of translation; G1/S transition of mitotic cell cycle
