Western Blot (WB)
(Western blot analysis of TRIM69 using HeLa whole cell lysates)
Rabbit anti-Human TRIM69 Polyclonal Antibody | anti-TRIM69 antibody
TRIM69 Antibody
Gene Names
TRIM69; Trif; HSD34; RNF36; HSD-34
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TRIM69; Polyclonal Antibody; TRIM69 Antibody; E3 ubiquitin protein ligase TRIM69; HSD34; RFP like domain containing protein trimless; RFP-like domain-containing protein trimless; RING finger protein 36; RNF36; TRI69_HUMAN; Trif; Trim69; Trimless; Tripartite motif containing 69; tripartite motif containing protein 69; tripartite motif protein 69; Tripartite motif-containing protein 69; anti-TRIM69 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
TRIM69 antibody detects endogenous levels of total TRIM69
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
296
Applicable Applications for anti-TRIM69 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human TRIM69
Subcellular Location
Nucleus Speckle
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of TRIM69 using HeLa whole cell lysates)
Western Blot (WB)
(Western blot analysis of TRIM69 using HeLa whole cell lysates)
Related Product Information for anti-TRIM69 antibody
Function: May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.
Subunit Structure: Interacts with PML.
Post-translational Modifications: Phosphorylated. Phosphorylation is necessary for nuclear localization.
Similarity: The RING-type zinc finger domain is responsible for E3 ubiquitin ligase activity and for nuclear localization and aggregation. Belongs to the TRIM/RBCC family.
Subunit Structure: Interacts with PML.
Post-translational Modifications: Phosphorylated. Phosphorylation is necessary for nuclear localization.
Similarity: The RING-type zinc finger domain is responsible for E3 ubiquitin ligase activity and for nuclear localization and aggregation. Belongs to the TRIM/RBCC family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 57 kDa
Predicted: 58 kDa
Predicted: 58 kDa
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM69 isoform c
NCBI Official Synonym Full Names
tripartite motif containing 69
NCBI Official Symbol
TRIM69
NCBI Official Synonym Symbols
Trif; HSD34; RNF36; HSD-34
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM69
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM69
Protein Family
UniProt Gene Name
TRIM69
UniProt Synonym Gene Names
RNF36
NCBI Description
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis.
Research Articles on TRIM69
Similar Products
Product Notes
The TRIM69 trim69 (Catalog #AAA9608596) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIM69 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRIM69 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the TRIM69 trim69 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIM69, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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