Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): 231 and hepg2 cellAmount of lysate: 40ug per lane Primary antibody: 1/400 dilution Secondary antibody dilution: 1/8000Exposure time: 1 minute)
Rabbit anti-Human TRIM62 Polyclonal Antibody | anti-TRIM62 antibody
TRIM62 Antibody
Gene Names
TRIM62; DEAR1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
TRIM62; Polyclonal Antibody; TRIM62 Antibody; DEAR1; anti-TRIM62 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TRIM62 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.8 mg/ml (varies by lot)
Sequence Length
475
Applicable Applications for anti-TRIM62 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the N terminal of human tripartite motif containing 62
Target Name
TRIM62
Preparation and Storage
Store at -20 degree C
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): 231 and hepg2 cellAmount of lysate: 40ug per lane Primary antibody: 1/400 dilution Secondary antibody dilution: 1/8000Exposure time: 1 minute)
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): 231 and hepg2 cellAmount of lysate: 40ug per lane Primary antibody: 1/400 dilution Secondary antibody dilution: 1/8000Exposure time: 1 minute)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/30.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/30.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/30.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/30.)
Related Product Information for anti-TRIM62 antibody
TRIM62 (tripartite motif-containing 62) is a 475 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. TRIM62 contains one B box-type zinc finger, one SPRY domain and one RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. As a member of the TRIM/RBCC family, TRIM62 may function in transcriptional regulation, cell transformation and carcinogenesis. In addition, TRIM62 expression can affect the entry of murine leukemia virus (MLV) and human immunodeficiency virus 1 (HIV).
Product Categories/Family for anti-TRIM62 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,490 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM62
NCBI Official Synonym Full Names
tripartite motif containing 62
NCBI Official Symbol
TRIM62
NCBI Official Synonym Symbols
DEAR1
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM62
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM62
Protein Family
UniProt Gene Name
TRIM62
UniProt Entry Name
TRI62_HUMAN
Uniprot Description
TRIM62: Belongs to the TRIM/RBCC family.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 1p35.1
Cellular Component: cytosol
Molecular Function: zinc ion binding; ligase activity
Biological Process: negative regulation of viral transcription; positive regulation of I-kappaB kinase/NF-kappaB cascade; cytokine and chemokine mediated signaling pathway; protein ubiquitination; innate immune response; positive regulation of transcription factor activity; regulation of virion penetration into host cell; activation of NF-kappaB transcription factor
Research Articles on TRIM62
Similar Products
Product Notes
The TRIM62 trim62 (Catalog #AAA9400870) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIM62 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRIM62 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the TRIM62 trim62 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIM62, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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