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Western Blot (WB) (Western Blot: Sample: Human Placenta lysate; Primary Ab: 3ug/ml Rabbit Anti-Human TREM1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody; ( MBS2086047 ))

Rabbit Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) Polyclonal Antibody | anti-TREM1 antibody

Polyclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 1 (TREM1)

Gene Names
TREM1; CD354; TREM-1
Reactivity
Homo sapiens (Human)
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Triggering Receptor Expressed On Myeloid Cells 1 (TREM1); Polyclonal Antibody; Polyclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 1 (TREM1); anti-TREM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Homo sapiens (Human)
Clonality
Polyclonal
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TREM1 antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes
Western blotting: 0.5-3ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
Optimal working dilutions must be determined by end user.
Source
Polyclonal antibody preparation
Traits
Liquid
Cross Reactivity
Rat
Immunogen
Recombinant TREM1 (Ala21~Asn205) expressed in E.coli ( MBS2018423 ).
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot: Sample: Human Placenta lysate; Primary Ab: 3ug/ml Rabbit Anti-Human TREM1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody; ( MBS2086047 ))

Western Blot (WB) (Western Blot: Sample: Human Placenta lysate; Primary Ab: 3ug/ml Rabbit Anti-Human TREM1 Antibody;Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody; ( MBS2086047 ))

Western Blot (WB)

(Western Blot: Sample: Recombinant TREM1, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant TREM1, Human.)

Immunohistochemistry (IHC)

(DAB staining on fromalin fixed paraffin-embedded Liver tissue))

Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin-embedded Liver tissue))

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Stomach Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Stomach Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
triggering receptor expressed on myeloid cells 1 isoform 2
NCBI Official Synonym Full Names
triggering receptor expressed on myeloid cells 1
NCBI Official Symbol
TREM1
NCBI Official Synonym Symbols
CD354; TREM-1
NCBI Protein Information
triggering receptor expressed on myeloid cells 1
UniProt Protein Name
Triggering receptor expressed on myeloid cells 1
UniProt Gene Name
TREM1
UniProt Synonym Gene Names
TREM-1

NCBI Description

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

Uniprot Description

TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: extracellular region; integral component of membrane; intracellular; plasma membrane

Molecular Function: receptor activity

Biological Process: humoral immune response; innate immune response; leukocyte migration; regulation of immune response

Research Articles on TREM1

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Product Notes

The TREM1 trem1 (Catalog #AAA2016030) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-3ug/mL Immunohistochemistry: 5-30ug/mL Immunocytochemistry: 5-30ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the TREM1 trem1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Triggering Receptor Expressed On Myeloid Cells 1 (TREM1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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