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Goat Transmembrane protein 37 Polyclonal Antibody | anti-TMEM37 antibody

Goat anti-Transmembrane protein 37 Antibody

Gene Names
TMEM37; PR; PR1
Reactivity
Expected from sequence similarity: Human
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Transmembrane protein 37; Polyclonal Antibody; Goat anti-Transmembrane protein 37 Antibody; TMEM37; transmembrane protein 37; CACNG5; PR; PR1; voltage-dependent calcium channel gamma subunit-like protein; TMEM37 antibody; transmembrane protein 37 antibody; CACNG5 antibody; PR antibody; PR1 antibody; voltage-dependent calcium channel gamma subunit-like protein antibody; anti-TMEM37 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
TNQTICFRDLGQ
Sequence Length
190
Applicable Applications for anti-TMEM37 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave an approx 26-28kDa band in Human Brain (Cerebellum, Frontal Cortex and Hippocampus) lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 20.9kDa according to NP_899063.2. The 26-28kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence TNQTICFRDLGQ, from the internal region of the protein sequence according to NP_899063.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,932 Da
NCBI Official Full Name
voltage-dependent calcium channel gamma-like subunit
NCBI Official Synonym Full Names
transmembrane protein 37
NCBI Official Symbol
TMEM37
NCBI Official Synonym Symbols
PR; PR1
NCBI Protein Information
voltage-dependent calcium channel gamma-like subunit
UniProt Protein Name
Voltage-dependent calcium channel gamma-like subunit
UniProt Gene Name
TMEM37
UniProt Entry Name
CCGL_HUMAN

Uniprot Description

TMEM37: Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

Protein type: Channel, calcium; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q14.2

Cellular Component: integral to membrane

Molecular Function: calcium channel activity; voltage-gated ion channel activity

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Product Notes

The TMEM37 tmem37 (Catalog #AAA420600) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Transmembrane protein 37 Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transmembrane protein 37 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments gave an approx 26-28kDa band in Human Brain (Cerebellum, Frontal Cortex and Hippocampus) lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 20.9kDa according to NP_899063.2. The 26-28kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the TMEM37 tmem37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TNQTICFRDL GQ. It is sometimes possible for the material contained within the vial of "Transmembrane protein 37, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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