Western Blot (WB)
(Western Blot: Sample: Mouse Kidney Tissue.)
Rabbit anti-Human Transmembrane Protein 27 (TMEM27) Polyclonal Antibody | anti-TMEM27 antibody
Polyclonal Antibody to Transmembrane Protein 27 (TMEM27)
MGHHHHHHSGSEF- CQPG AENAFKVRLS IRTALGDKAY AWDTNEEYLF KAMVAFSMRK VPNREATEIS HVLLCNVTQR VSFWFVVTDP SKNHTLPAVE VQSAIRMNKN RINNAFFLND QTLEFLKIPS TLAPPMD
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Mouse Kidney Tissue.)
Western Blot (WB)
(Western Blot: Sample: Mouse Kidney Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant TMEM27, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant TMEM27, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
Uniprot Description
TMEM27: Regulator of SNARE complex function. Stimulator of beta cell replication. Belongs to the TMEM27 family.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: brush border membrane; cytoplasm; integral component of membrane
Molecular Function: metallopeptidase activity; peptidyl-dipeptidase activity; protein binding
Biological Process: positive regulation of amino acid transport; positive regulation of calcium ion-dependent exocytosis; proteolysis
Research Articles on TMEM27
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Product Notes
The TMEM27 tmem27 (Catalog #AAA2003169) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Transmembrane Protein 27 (TMEM27) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transmembrane Protein 27 (TMEM27) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the TMEM27 tmem27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- CQPG AENAFKVRLS IRTALGDKAY AWDTNEEYLF KAMVAFSMRK VPNREATEIS HVLLCNVTQR VSFWFVVTDP SKNHTLPAVE VQSAIRMNKN RINNAFFLND QTLEFLKIPS TLAPPMD. It is sometimes possible for the material contained within the vial of "Transmembrane Protein 27 (TMEM27), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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