Western Blot (WB)
(Western Blot: Sample: Human HepG2 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Rat TGFbR3 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Rat Transforming Growth Factor Beta Receptor III Polyclonal Antibody | anti-TGFbR3 antibody
Polyclonal Antibody to Transforming Growth Factor Beta Receptor III (TGFbR3)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- N YLAEYLQPKA AEGCVLPSQP HEKEVHIIEL ITPSSNPYSA FQVDIIVDIR PAQEDPEVVK NLVLILKCKK SVNWVIKSFD VKGNLKVIAP NSIGFGKESE RSMTMTKLVR DDIPSTQENL MKWALDNGYR PVTSYTMAPV ANRFHLRLEN NEEMRDEEVH TIPPELRILL DPDHPPALDN PLFPGEGSPN GGLPFPFPDI
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Human HepG2 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Rat TGFbR3 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Human HepG2 cell lysate; Primary Ab: 2ug/ml Rabbit Anti-Rat TGFbR3 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Rat Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Rat Tissue))
NCBI and Uniprot Product Information
NCBI Description
binds TGF-beta; may regulate TGF-beta receptor type II expression or ligand-binding activity [RGD, Feb 2006]
Uniprot Description
TGFBR3: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Interacts with TCTEX1D4. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 14p22
Cellular Component: cell surface; cytoplasm; endoplasmic reticulum; external side of plasma membrane; extracellular matrix; extracellular space; integral component of membrane; integral component of plasma membrane; proteinaceous extracellular matrix; receptor complex
Molecular Function: activin binding; coreceptor activity; fibroblast growth factor binding; glycosaminoglycan binding; heparin binding; PDZ domain binding; protein binding; SMAD binding; transforming growth factor beta binding; transforming growth factor beta receptor binding; transforming growth factor beta-activated receptor activity; type II transforming growth factor beta receptor binding
Biological Process: blastocyst development; blood vessel development; blood vessel remodeling; BMP signaling pathway; cardiac muscle cell proliferation; cell growth; collagen metabolic process; epithelial to mesenchymal transition; immune response; in utero embryonic development; liver development; negative regulation of cell motility; negative regulation of epithelial cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway; organ regeneration; osteoblast differentiation; palate development; positive regulation of BMP signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation; positive regulation of NF-kappaB transcription factor activity; positive regulation of transforming growth factor beta receptor signaling pathway; protein complex assembly; regulation of JNK cascade; regulation of protein binding; response to follicle-stimulating hormone stimulus; response to hypoxia; signal transduction; transforming growth factor beta receptor complex assembly; transforming growth factor beta receptor signaling pathway; vasculogenesis; ventricular cardiac muscle tissue morphogenesis
Research Articles on TGFbR3
Similar Products
Product Notes
The TGFbR3 tgfbr3 (Catalog #AAA2026234) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Transforming Growth Factor Beta Receptor III (TGFbR3) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Transforming Growth Factor Beta Receptor III can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the TGFbR3 tgfbr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- N YLAEYLQPKA AEGCVLPSQP HEKEVHIIEL ITPSSNPYSA FQVDIIVDIR PAQEDPEVVK NLVLILKCKK SVNWVIKSFD VKGNLKVIAP NSIGFGKESE RSMTMTKLVR DDIPSTQENL MKWALDNGYR PVTSYTMAPV ANRFHLRLEN NEEMRDEEVH TIPPELRILL DPDHPPALDN PLFPGEGSPN GGLPFPFPDI. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor Beta Receptor III, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
