Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney using MBS1489141 at dilution of 1:20)
Rabbit anti-Human Transforming growth factor beta-3 Polyclonal Antibody | anti-TGFB3 antibody
Rabbit anti-human Transforming growth factor beta-3 polyclonal Antibody
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney using MBS1489141 at dilution of 1:20)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney using MBS1489141 at dilution of 1:20)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Mar 2009]
Uniprot Description
TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family.
Protein type: Motility/polarity/chemotaxis; Cell development/differentiation; Secreted, signal peptide; Secreted; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: 14q24
Cellular Component: cell soma; cell surface; extracellular matrix; extracellular region; extracellular space; nucleus; plasma membrane; proteinaceous extracellular matrix; T-tubule
Molecular Function: cytokine activity; growth factor activity; identical protein binding; protein binding; protein heterodimerization activity; punt binding; transforming growth factor beta binding
Biological Process: activation of MAPK activity; aging; alveolus development; blood coagulation; cell development; cell growth; embryonic neurocranium morphogenesis; extracellular matrix organization and biogenesis; female pregnancy; gut development; in utero embryonic development; inner ear development; intercellular junction assembly and maintenance; mammary gland development; negative regulation of cell proliferation; negative regulation of DNA replication; negative regulation of neuron apoptosis; negative regulation of transforming growth factor beta receptor signaling pathway; odontogenesis; palate development; platelet activation; platelet degranulation; positive regulation of apoptosis; positive regulation of bone mineralization; positive regulation of cell division; positive regulation of collagen biosynthetic process; positive regulation of DNA replication; positive regulation of filopodium formation; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of cell proliferation; regulation of MAPKKK cascade; response to estrogen stimulus; response to hypoxia; response to progesterone stimulus; salivary gland morphogenesis; SMAD protein nuclear translocation; transforming growth factor beta receptor signaling pathway; uterine wall breakdown
Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 1; Rienhoff Syndrome
Research Articles on TGFB3
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Product Notes
The TGFB3 tgfb3 (Catalog #AAA1489141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Transforming growth factor beta-3 polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transforming growth factor beta-3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TGFB3 tgfb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transforming growth factor beta-3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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