Western Blot (WB)
(Western blot analysis of TRAF6 in 3T3 cell lysate (Lane 1) and in Jurkat cell lysate (Lane 2& 3).)
Rabbit TRAF6 Polyclonal Antibody | anti-TRAF6 antibody
TRAF6 Antibody
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
TRAF6; Polyclonal Antibody; TRAF6 Antibody; Rabbit Polyclonal TRAF6 Antibody; Polyclonal TRAF6 antibody; anti-TRAF6 antibody; RNF85 antibody; TRAF-6 antibody; TRAF 6; TRAF 6 antibody; TRAF-6; MGC:3310 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer containing 30% Glycerol, 0.5% BSA, and 0.01% Thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
359
Applicable Applications for anti-TRAF6 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Immunogen
TRAF6 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 436 of rat TRAF6 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of TRAF6 in 3T3 cell lysate (Lane 1) and in Jurkat cell lysate (Lane 2& 3).)
Western Blot (WB)
(Western blot analysis of TRAF6 in 3T3 cell lysate (Lane 1) and in Jurkat cell lysate (Lane 2& 3).)
Related Product Information for anti-TRAF6 antibody
TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs. Recently it has been shown that TRANCE/OPGL activates the antiapoptotic serine/threonine kinase Akt/PKB through a signaling complex involving c-Src and TRAF6. Mice deficient in TRAF6 are osteopetrotic with defects in bone remodeling and tooth eruption due to impaired osteoclast function. Like TRAF2 and TRAF3, TRAF6 is also essential for perinatal and postnatal survival. These findings establish diverse and critical roles for TRAF6 in perinatal and postnatal survival, bone metabolism, LPS, and cytokine signaling.
Product Categories/Family for anti-TRAF6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
TRAF6
NCBI Official Symbol
LOC100862757
NCBI Protein Information
TRAF6
Protein Family
Similar Products
Product Notes
The TRAF6 (Catalog #AAA5311366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TRAF6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the TRAF6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAF6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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