Rabbit anti-Human TRA2B Polyclonal Antibody | anti-TRA2B antibody

TRA2B, ID (TRA2B, SFRS10, Transformer-2 protein homolog beta, Splicing factor, arginine/serine-rich 10, Transformer-2 protein homolog B) (FITC)

Cat. Num. AAA6357816

• Gene Names: TRA2B; SFRS10; SRFS10; TRAN2B; PPP1R156; TRA2-BETA; Htra2-beta
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TRA2B; Polyclonal Antibody; ID (TRA2B; SFRS10; Transformer-2 protein homolog beta; Splicing factor; arginine/serine-rich 10; Transformer-2 protein homolog B) (FITC); Transformer-2 protein homolog B; anti-TRA2B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 288

• Applicable Applications for anti-TRA2B antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: TRA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human TRA2B.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TRA2B Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TRA2B antibody detected the TRA2B protein (arrow).)

Immunohistochemistry (IHC)

(TRA2B Antibody (Center) (AP14688c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRA2B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-TRA2B antibody

TRA2B is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.

Product Categories/Family for anti-TRA2B antibody

Antibodies; Splicing Factors

References

Benderska, N., et al. Biochim. Biophys. Acta 1799 (5-6), 448-453 (2010): Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009). Caporaso, N., et al. PLoS ONE 4 (2), E4653 (2009): Gabriel, B., et al. Acta Obstet Gynecol Scand 88(2):216-221(2009). Miele, A., et al. J. Cell. Biochem. 102(1):136-148(2007).

NCBI and Uniprot Product Information

• NCBI GI #: 4759098
• NCBI GeneID: 6434
• NCBI Accession #: NP_004584.1
• NCBI GenBank Nucleotide #: NP_004584.1
• UniProt Accession #: P62995
• NCBI Official Full Name: transformer-2 protein homolog beta isoform 1
• NCBI Official Synonym Full Names: transformer 2 beta homolog
• NCBI Official Symbol: TRA2B
• NCBI Official Synonym Symbols: SFRS10; SRFS10; TRAN2B; PPP1R156; TRA2-BETA; Htra2-beta
• NCBI Protein Information: transformer-2 protein homolog beta
• UniProt Protein Name: Transformer-2 protein homolog beta
• Protein Family: Transformer-2 protein
• UniProt Gene Name: TRA2B
• UniProt Synonym Gene Names: SFRS10; TRA-2 beta; TRA2-beta; hTRA2-beta
• UniProt Entry Name: TRA2B_HUMAN

NCBI Description

This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]