Western Blot (WB)
(Fig.1. Western blot analysis of SH-SY5Y 293T Mouse-kidney lysis using TP53INP2 antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000.)
Rabbit anti-Human TP53INP2 Polyclonal Antibody | anti-TP53INP2 antibody
TP53INP2 Polyclonal Antibody
IHC-P: 1:100-1:300
ELISA: 1:10000
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Western Blot (WB)
(Fig.1. Western blot analysis of SH-SY5Y 293T Mouse-kidney lysis using TP53INP2 antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000.)
Western Blot (WB)
(Fig.1. Western blot analysis of SH-SY5Y 293T Mouse-kidney lysis using TP53INP2 antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000.)
Immunohistochemistry (IHC)
(Fig.2. Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200.)
Immunohistochemistry (IHC)
(Fig.2. Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200.)
Immunohistochemistry (IHC)
(Fig.3. Immunohistochemical analysis of paraffin-embedded human-lungcancer, antibody was diluted at 1:200.)
Immunohistochemistry (IHC)
(Fig.3. Immunohistochemical analysis of paraffin-embedded human-lungcancer, antibody was diluted at 1:200.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016]
Uniprot Description
TP53INP2: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Chromosomal Location of Human Ortholog: 20q11.22
Cellular Component: PML body; autophagic vacuole; cytoplasmic vesicle; cytosol; nucleus
Molecular Function: protein binding
Biological Process: osteoblast differentiation; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of autophagy; autophagic vacuole formation
Research Articles on TP53INP2
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Product Notes
The TP53INP2 tp53inp2 (Catalog #AAA9708048) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TP53INP2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TP53INP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). WB: 1:500-1:2000 IHC-P: 1:100-1:300 ELISA: 1:10000. Researchers should empirically determine the suitability of the TP53INP2 tp53inp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TP53INP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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