Testing Data
Rabbit TP2 Polyclonal Antibody | anti-TP2 antibody
TP2 Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
TP2; Polyclonal Antibody; TP2 Antibody; Telomerase reverse transcriptase; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TEAP; anti-TP2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-TP2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
138
Applicable Applications for anti-TP2 antibody
Western Blot (WB)
Application Notes
Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
Immunogen
Synthetic peptide surrounding amino acid 572 of human TP2.
Positive Control
3T3 cell lysate
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-TP2 antibody
Background: Telomerase is an RNA-dependant DNA polymerase that catalyzes the addition of telemoric repeat, TTAGGG to chromosome ends. Telomerase is composed of an internal telomerase RNA template (TERC) and the enzyme, telomerase reverse transcriptase (TERT or TP2). Telomerase expression is usually repressed in postnatal somatic cells resulting in shortening of telomeres. Overexpression of telomerase may be implicated with oncogenesis.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
15,641 Da
NCBI Official Full Name
transition protein 2
UniProt Protein Name
Nuclear transition protein 2
UniProt Gene Name
TNP2
UniProt Synonym Gene Names
TP-2; TP2
UniProt Entry Name
STP2_HUMAN
Uniprot Description
TP2: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 2 family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16p13.13
Cellular Component: nucleosome; nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: sperm motility; binding of sperm to zona pellucida; multicellular organismal development; acrosome reaction; penetration of zona pellucida; spermatogenesis; cell differentiation
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Product Notes
The TP2 tnp2 (Catalog #AAA840918) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control. Researchers should empirically determine the suitability of the TP2 tnp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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