Rabbit anti-Human TOX4 Polyclonal Antibody | anti-TOX4 antibody

TOX4, NT (TOX4, C14orf92, KIAA0737, TOX high mobility group box family member 4, Epidermal Langerhans cell protein LCP1) (Azide free) (HRP)

Cat. Num. AAA6357487

• Gene Names: TOX4; LCP1; MIG7; C14orf92; KIAA0737
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TOX4; Polyclonal Antibody; NT (TOX4; C14orf92; KIAA0737; TOX high mobility group box family member 4; Epidermal Langerhans cell protein LCP1) (Azide free) (HRP); Epidermal Langerhans cell protein LCP1; anti-TOX4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-TOX4 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the N-terminal region of human TOX4.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TOX4 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the TOX4 antibody detected the TOX4 protein (arrow).)

Related Product Information for anti-TOX4 antibody

TOX4 (TOX high mobility group box family member 4) contains 1 HMG box DNA-binding domain and the function remains unknown.

Product Categories/Family for anti-TOX4 antibody

Antibodies; KIAA; orf

References

Lee, J.H., et al. J. Biol. Chem. 285(32):24466-24476(2010). Lee, S.J., et al. Exp. Mol. Med. 41(3):189-200(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Lim, J., et al. Cell 125(4):801-814(2006). Colland, F., et al. Genome Res. 14(7):1324-1332(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 7662274
• NCBI GeneID: 9878
• NCBI Accession #: NP_055643.1
• NCBI GenBank Nucleotide #: NM_014828.2
• UniProt Accession #: O94842; B4DPY8; B4DSM0; E7EV69
• Molecular Weight: 66,195 Da
• NCBI Official Full Name: TOX high mobility group box family member 4
• NCBI Official Synonym Full Names: TOX high mobility group box family member 4
• NCBI Official Symbol: TOX4
• NCBI Official Synonym Symbols: LCP1; MIG7; C14orf92; KIAA0737
• NCBI Protein Information: TOX high mobility group box family member 4; migration-inducing protein 7; epidermal Langerhans cell protein LCP1
• UniProt Protein Name: TOX high mobility group box family member 4
• Protein Family: TOX high mobility group box family
• UniProt Gene Name: TOX4
• UniProt Synonym Gene Names: C14orf92; KIAA0737
• UniProt Entry Name: TOX4_HUMAN

Uniprot Description

TOX4: Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm; chromatin

Molecular Function: protein binding; DNA binding; chromatin binding

Biological Process: chromatin remodeling; regulation of transcription, DNA-dependent