Western Blot (WB)
(Western Blot (WB) analysis of TNS3 polyclonal antibody at 1:500 dilutionLane1:H9C2 whole cell lysate (40ug) Lane2:NIH-3T3 whole cell lysate (40ug) Lane3:DLD whole cell lysate (40ug))
Rabbit TNS3 Polyclonal Antibody | anti-TNS3 antibody
TNS3 Polyclonal Antibody
Gene Names
TNS3; TEM6; TENS1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
TNS3; Polyclonal Antibody; TNS3 Polyclonal Antibody; Tensin-3; Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6; anti-TNS3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TNS3 polyclonal antibody detects endogenous levels of TNS3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
1445
Applicable Applications for anti-TNS3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 535-580 of Human TNS3.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of TNS3 polyclonal antibody at 1:500 dilutionLane1:H9C2 whole cell lysate (40ug) Lane2:NIH-3T3 whole cell lysate (40ug) Lane3:DLD whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of TNS3 polyclonal antibody at 1:500 dilutionLane1:H9C2 whole cell lysate (40ug) Lane2:NIH-3T3 whole cell lysate (40ug) Lane3:DLD whole cell lysate (40ug))
Related Product Information for anti-TNS3 antibody
The Tensin (Tns) family of proteins is involved in the maintenance of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities. Tns proteins also contain a Src homology 2 (SH2) domain and have the ability to be phosphorylated, suggesting a role in signal transduction cascades. These diverse characteristics indicate that Tns proteins may be important links between the cytoskeleton and signal transduction pathways. Tns3, also known as TEM6 or TENS1, localizes to the focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but can also be found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle and white blood cells. Tns3 is essential for proper growth and development, as suggested by growth retardation and death in a number of Tns3-/- mice.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 155kDa
NCBI Official Full Name
tensin-3
NCBI Official Synonym Full Names
tensin 3
NCBI Official Symbol
TNS3
NCBI Official Synonym Symbols
TEM6; TENS1
NCBI Protein Information
tensin-3
UniProt Protein Name
Tensin-3
Protein Family
UniProt Gene Name
TNS3
UniProt Synonym Gene Names
TEM6; TENS1; TPP
Uniprot Description
May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development ().
Research Articles on TNS3
Similar Products
Product Notes
The TNS3 tns3 (Catalog #AAA3007358) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNS3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TNS3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the TNS3 tns3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
