Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7052941 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human TNPO3 Polyclonal Antibody | anti-TNPO3 antibody
TNPO3 Antibody
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7052941 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7052941 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
Uniprot Description
IPO3: Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Karyopherin; Nuclear export; Nuclear import; Receptor, misc.
Chromosomal Location of Human Ortholog: 7q32.1
Cellular Component: cytoplasm; intracellular membrane-bound organelle; nuclear membrane
Molecular Function: identical protein binding; nuclear localization sequence binding; protein binding; protein transporter activity; receptor activity
Biological Process: splicing factor protein import into nucleus
Disease: Muscular Dystrophy, Limb-girdle, Type 1f
Research Articles on TNPO3
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Product Notes
The TNPO3 tnpo3 (Catalog #AAA7052941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNPO3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNPO3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF). IF: 1:50-1:200. Researchers should empirically determine the suitability of the TNPO3 tnpo3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNPO3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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