Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7049316 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human TNP1 Polyclonal Antibody | anti-TNP1 antibody
TNP1 Antibody
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7049316 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7049316 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]
Uniprot Description
TP1: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 1 family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 2q35-q36
Cellular Component: male germ cell nucleus; nucleosome
Molecular Function: DNA binding; protein binding
Biological Process: chromatin remodeling; chromatin silencing; fertilization, exchange of chromosomal proteins; negative regulation of transcription, DNA-dependent; nucleosome disassembly; sexual reproduction; single strand break repair; sperm motility; spermatid development; spermatid nuclear differentiation; spermatid nuclear elongation
Research Articles on TNP1
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Product Notes
The TNP1 tnp1 (Catalog #AAA7049316) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF). IF: 1: 50-1: 200. Researchers should empirically determine the suitability of the TNP1 tnp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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