Western Blot (WB)
(MBS421855(0.5ug/ml) staining of Human Pancreas Lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.)
Goat TMPRSS2 Polyclonal Antibody | anti-TMPRSS2 antibody
Goat anti-TMPRSS2 Antibody
Western blot: Approx 55-60kDa band observed in Human Pancreas and Kidney lysates (calculated MW of 53.9kDa according to NP_005647.2). This molecular weight is routinely observed by other sources. Recommended concentration: 0.1-0.5ug/ml. Primary incubation 1 hour at room temperature.
Western Blot (WB)
(MBS421855(0.5ug/ml) staining of Human Pancreas Lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.)
Western Blot (WB)
(MBS421855(0.5ug/ml) staining of Human Pancreas Lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Uniprot Description
TMPRSS2: a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Protein type: Protease; Membrane protein, integral; EC 3.4.21.-
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding; scavenger receptor activity; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: positive regulation of virion penetration into host cell; protein autoprocessing; proteolysis; receptor-mediated endocytosis
Research Articles on TMPRSS2
Similar Products
Product Notes
The TMPRSS2 tmprss2 (Catalog #AAA421855) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-TMPRSS2 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMPRSS2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 55-60kDa band observed in Human Pancreas and Kidney lysates (calculated MW of 53.9kDa according to NP_005647.2). This molecular weight is routinely observed by other sources. Recommended concentration: 0.1-0.5ug/ml. Primary incubation 1 hour at room temperature. Researchers should empirically determine the suitability of the TMPRSS2 tmprss2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TDWIYRQMRA DG. It is sometimes possible for the material contained within the vial of "TMPRSS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
