Rabbit anti-Human, Mouse TMEM55A Polyclonal Antibody | anti-TMEM55A antibody

TMEM55A Antibody

Cat. Num. AAA1498738

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G Purified
• Synonyms: TMEM55A; Polyclonal Antibody; TMEM55A Antibody; Type 2 phosphatidylinositol 4; 5-bisphosphate 4-phosphatase (EC:3.1.3.78); Type 2 PtdIns-4; 5-P2 4-Ptase; PtdIns-4; 5-P2 4-Ptase II; Transmembrane protein 55A; anti-TMEM55A antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G Purified
• Sequence Length: 257

• Applicable Applications for anti-TMEM55A antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Recommended dilution: WB:1:500-2000; IHC:1:20-1:200
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugate: Non-conjugated
• Immunogen: Recombinant human Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase protein
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87457 / sc-87458
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: TMEM55A antibody at 5ug/ml+ Mouse liver tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 28 kDaObserved band size: 28 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using MBS1498738 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of LO2 cells using MBS1498738 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-TMEM55A antibody

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.

NCBI and Uniprot Product Information

• NCBI GI #: 24308165
• NCBI GeneID: 55529
• NCBI Accession #: NP_061180.1
• NCBI GenBank Nucleotide #: NM_018710.2
• UniProt Accession #: Q8N4L2; Q68CU2; B2R9H4
• Molecular Weight: 28,081 Da
• NCBI Official Full Name: type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
• NCBI Official Synonym Full Names: transmembrane protein 55A
• NCBI Official Symbol: TMEM55A
• NCBI Protein Information: type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
• UniProt Protein Name: Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
• Protein Family: Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase
• UniProt Gene Name: TMEM55A
• UniProt Synonym Gene Names: Type 2 PtdIns-4,5-P2 4-Ptase
• UniProt Entry Name: TM55A_HUMAN

NCBI Description

TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008]

Uniprot Description

TMEM55A: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; EC 3.1.3.78; Phosphatase, lipid

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: integral to membrane; late endosome membrane; lysosomal membrane

Biological Process: phosphoinositide dephosphorylation