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Western Blot (WB) (Western blot analysis of extracts from LOVO cells, using TM16G antiobdy.)

Rabbit anti-Human TM16G Polyclonal Antibody | anti-TM16G antibody

TM16G Antibody

Gene Names
ANO7; NGEP; DTMPP; IPCA5; D-TMPP; IPCA-5; PCANAP5; TMEM16G; PCANAP5L
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TM16G; Polyclonal Antibody; TM16G Antibody; New gene expressed in prostate; Prostate cancer-associated protein 5; IPCA-5; Dresden-transmembrane protein of the prostate; D-TMPP; anti-TM16G antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TM16G protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
179
Applicable Applications for anti-TM16G antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from C-terminal of human TM16G.
Target Name
TM16G
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from LOVO cells, using TM16G antiobdy.)

Western Blot (WB) (Western blot analysis of extracts from LOVO cells, using TM16G antiobdy.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using TM16G antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using TM16G antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HepG2 cells, using TM16G antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of HepG2 cells, using TM16G antibody.)
Related Product Information for anti-TM16G antibody
Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions.Bera T.K., Proc. Natl. Acad. Sci. U.S.A. 101:3059-3064(2004).Walker M.G., Genome Res. 9:1198-1203(1999).Katoh M., Int. J. Mol. Med. 14:759-764(2004).
Product Categories/Family for anti-TM16G antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
99,754 Da
NCBI Official Full Name
anoctamin-7 isoform NGEP-short
NCBI Official Synonym Full Names
anoctamin 7
NCBI Official Symbol
ANO7
NCBI Official Synonym Symbols
NGEP; DTMPP; IPCA5; D-TMPP; IPCA-5; PCANAP5; TMEM16G; PCANAP5L
NCBI Protein Information
anoctamin-7
UniProt Protein Name
Anoctamin-7
UniProt Gene Name
ANO7
UniProt Synonym Gene Names
NGEP; PCANAP5; TMEM16G; D-TMPP
UniProt Entry Name
ANO7_HUMAN

NCBI Description

This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]

Uniprot Description

ANO7: May act as a calcium-activated chloride channel. May play a role in cell-cell interactions. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Calcium-binding; Channel, chloride; Membrane protein, integral; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: endoplasmic reticulum; integral to membrane; plasma membrane; intracellular; cytosol; cell junction; nucleus

Molecular Function: phospholipid scramblase activity; intracellular calcium activated chloride channel activity

Biological Process: chloride transport; lipid transport; transmembrane transport

Research Articles on TM16G

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Product Notes

The TM16G ano7 (Catalog #AAA9402891) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TM16G Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TM16G can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 Immunofluorescence: 1:100~1:500. Researchers should empirically determine the suitability of the TM16G ano7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM16G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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