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Immunohistochemistry (IHC) (Human Prostate (formalin-fixed, paraffin-embedded) stained with TK1 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Rabbit anti-Human TK1 Polyclonal Antibody | anti-TK1 antibody

TK1, NT (Thymidine Kinase, Cytosolic)

Gene Names
TK1; TK2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
TK1; Polyclonal Antibody; NT (Thymidine Kinase; Cytosolic); Anti -TK1; anti-TK1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human TK1.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.
Applicable Applications for anti-TK1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1ug/ml
Western Blot: 1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Immunogen
Synthetic peptide corresponding to human TK1 at N-terminal (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Prostate (formalin-fixed, paraffin-embedded) stained with TK1 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC) (Human Prostate (formalin-fixed, paraffin-embedded) stained with TK1 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Product Categories/Family for anti-TK1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,469 Da
NCBI Official Full Name
thymidine kinase, cytosolic
NCBI Official Synonym Full Names
thymidine kinase 1, soluble
NCBI Official Symbol
TK1
NCBI Official Synonym Symbols
TK2
NCBI Protein Information
thymidine kinase, cytosolic; thymidine kinase-1; thymidine kinase 1 soluble isoform
UniProt Protein Name
Thymidine kinase, cytosolic
Protein Family
UniProt Gene Name
TK1
UniProt Entry Name
KITH_HUMAN

Uniprot Description

Catalytic activity: ATP + thymidine = ADP + thymidine 5'-phosphate.

Subunit structure: Homotetramer. Ref.13 Ref.15

Subcellular location: Cytoplasm.

Post-translational modification: Phosphorylated on Ser-13 in mitosis. Ref.7

Miscellaneous: Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.

Sequence similarities: Belongs to the thymidine kinase family.

Research Articles on TK1

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Product Notes

The TK1 tk1 (Catalog #AAA647313) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TK1, NT (Thymidine Kinase, Cytosolic) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TK1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: ELISA: 1ug/ml Western Blot: 1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml. Researchers should empirically determine the suitability of the TK1 tk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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