Rabbit anti-Human TIAM2 Polyclonal Antibody | anti-TIAM2 antibody

TIAM2 (T-lymphoma Invasion and Metastasis-inducing Protein 2, TIAM-2, KIAA2016, SIF and TIAM1-like Exchange Factor, STEF) (HRP)

Cat. Num. AAA6396515

• Gene Names: TIAM2; STEF; TIAM-2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TIAM2; Polyclonal Antibody; TIAM2 (T-lymphoma Invasion and Metastasis-inducing Protein 2; TIAM-2; KIAA2016; SIF and TIAM1-like Exchange Factor; STEF) (HRP); anti-TIAM2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TIAM2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Sequence Length: 2665

• Applicable Applications for anti-TIAM2 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length protein corresponding to aa1-626 from human TIAM2.
• Immunogen Sequence: MEGPRENQDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECFYETESHGKS
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of TIAM2 expression in K-562 using 134436.)

Western Blot (WB)

(Western Blot analysis of TIAM2 expression in transfected 293T cell line by 134436. Lane 1: TIAM2 transfected lysate (70.8kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-TIAM2 antibody

Antibodies; Cancer Markers

NCBI and Uniprot Product Information

• NCBI GI #: 1677530090
• NCBI GeneID: 26230
• NCBI Accession #: NM_001010927.3
• NCBI GenBank Nucleotide #: NM_001010927
• NCBI Official Full Name: Homo sapiens TIAM Rac1 associated GEF 2 (TIAM2), transcript variant 2, mRNA
• NCBI Official Synonym Full Names: TIAM Rac1 associated GEF 2
• NCBI Official Symbol: TIAM2
• NCBI Official Synonym Symbols: STEF; TIAM-2
• NCBI Protein Information: T-lymphoma invasion and metastasis-inducing protein 2
• Protein Family: T-lymphoma invasion and metastasis-inducing protein

NCBI Description

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]