Rabbit anti-Human THTPA Polyclonal Antibody | anti-THTPA antibody

THTPA (Thiamine-triphosphatase, ThTPase, THTP) (FITC)

Cat. Num. AAA6396492

• Gene Names: THTPA; THTP; THTPASE
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: THTPA; Polyclonal Antibody; THTPA (Thiamine-triphosphatase; ThTPase; THTP) (FITC); EC=3.6.1.28; MGC2652; anti-THTPA antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human THTPA.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 230

• Applicable Applications for anti-THTPA antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human THTPA, aa1-230 (NP_077304.1).
• Immunogen Sequence: MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQADHWLRRREDSGWELKCPGAAGVLGPHTEYKELTAEPTIVAQLCKVLRADGLGAGDVAAVLGPLGLQEVASFVTKRSAWKLVLLGADEEEPQLRVDLDTADFGYAVGEVEALVHEEAEVPTALEKIHRLSSMLGVPAQETAPAKLIVYLQRFRPQDYQRLLEVNSSRERPQETEDPDHCLG
• Conjugate: FITC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of THTPA expression in transfected 293T cell line by THTPA polyclonal antibody. Lane 1: THTPA transfected lysate (25.6kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-THTPA antibody

Antibodies; Vitamins

NCBI and Uniprot Product Information

• NCBI GI #: 13236577
• NCBI GeneID: 79178
• NCBI Accession #: NP_077304.1
• NCBI GenBank Nucleotide #: NM_024328.2
• UniProt Accession #: Q9BU02
• NCBI Official Full Name: thiamine-triphosphatase isoform 1
• NCBI Official Synonym Full Names: thiamine triphosphatase
• NCBI Official Symbol: THTPA
• NCBI Official Synonym Symbols: THTP; THTPASE
• NCBI Protein Information: thiamine-triphosphatase
• UniProt Protein Name: Thiamine-triphosphatase
• Protein Family: Thiamine-triphosphatase
• UniProt Gene Name: THTPA
• UniProt Synonym Gene Names: ThTPase
• UniProt Entry Name: THTPA_HUMAN

NCBI Description

This gene encodes an enzyme which catalyzes the biosynthesis of thiamine disphophate (vitamin B1) by hydrolysis of thiamine triphosphate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Uniprot Description

THTP: Hydrolase highly specific for thiamine triphosphate (ThTP). Belongs to the ThTPase family.

Protein type: Cofactor and Vitamin Metabolism - thiamine; EC 3.6.1.28; Hydrolase

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytosol

Molecular Function: thiamin-triphosphatase activity; hydrolase activity; magnesium ion binding

Biological Process: thiamin metabolic process; generation of precursor metabolites and energy; vitamin metabolic process; dephosphorylation; thiamin and derivative metabolic process; water-soluble vitamin metabolic process; thiamin diphosphate metabolic process