Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Mouse muscle tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
Rabbit anti-Human, Mouse THRA Polyclonal Antibody | anti-THRA antibody
THRA Antibody
Immunohistochemistry: 1:25-1:100
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Mouse muscle tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Mouse muscle tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute)
NCBI and Uniprot Product Information
Uniprot Description
TR-alpha: nuclear hormone receptor and transcription factor. High affinity receptor for triiodothyronine. Interacts with SRC-3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Four splice variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor; Transcription factor
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: cytosol; nucleoplasm; nucleus
Molecular Function: protein binding; protein domain specific binding; TATA-binding protein binding; thyroid hormone receptor activity; transcription factor activity; transcription factor binding
Biological Process: hormone-mediated signaling; negative regulation of transcription, DNA-dependent; negative regulation of transcriptional preinitiation complex assembly; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter
Disease: Hypothyroidism, Congenital, Nongoitrous, 6
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Product Notes
The THRA thra (Catalog #AAA9415232) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The THRA Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's THRA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the THRA thra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "THRA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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